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Chemical Structure| 607-34-1 Chemical Structure| 607-34-1

Structure of 607-34-1

Chemical Structure| 607-34-1

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Product Citations

Product Citations

Jang, Mingyeong ; Lim, Taeho ; Park, Byoung Yong ; Han, Min Su ;

Abstract: In this study, we developed a metal-free and highly chemoselective method for the reduction of aromatic nitro compounds. This reduction was performed using tetrahydroxydiboron [B2(OH)4] as the reductant and 4,4'-bipyridine as the organocatalyst and could be completed within 5 min at room temperature. Under optimal conditions, nitroarenes with sensitive functional groups, such as vinyl, ethynyl, carbonyl, and halogen, were converted into the corresponding anilines with excellent selectivity while avoiding the undesirable reduction of the sensitive functional groups.

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Product Details of [ 607-34-1 ]

CAS No. :607-34-1
Formula : C9H6N2O2
M.W : 174.16
SMILES Code : O=[N+](C1=C2C=CC=NC2=CC=C1)[O-]
MDL No. :MFCD00006790
InChI Key :NDDZXHOCOKCNBM-UHFFFAOYSA-N
Pubchem ID :11829

Safety of [ 607-34-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 607-34-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 607-34-1 ]

[ 607-34-1 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 607-34-1 ]
  • [ 36887-98-6 ]
YieldReaction ConditionsOperation in experiment
76% With tetrahydroxydiboron; water; at 80℃; for 8h; General procedure: Nitro aromatic (1.0 mmol), B2(OH)4 (5.0 equiv, 5.0 mmol), and H2O (3.0 mL) were added in a10 mL tube. The reaction mixture was stirred at 80 C for 8 h. When the reaction was completemonitored by TLC, the mixture was cooled to room temperature, extracted with ethyl acetate (3 ×20 mL). The combined organic phase was dried over anhydrous Na2SO4, filtered, andconcentrated under reduced pressure. The residue was purified by silica gel columnchromatography.
  • 5
  • [ 607-34-1 ]
  • [ 160893-04-9 ]
 

Historical Records

Categories

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