Home Chemistry Heterocyclic Building Blocks Pyridines 2-Chloro-5-Iodopyridine
Nucleophilic substitution: The chlorine atom in 2-chloro-5-iodopyridine can undergo nucleophilic substitution reactions, where it can be replaced by a nucleophile. This could include reactions with amines, thiols, or other nucleophilic species.
Metal-catalyzed cross-coupling reactions: The iodine atom in 2-chloro-5-iodopyridine can undergo palladium-catalyzed cross-coupling reactions with suitable coupling partners such as aryl or vinyl halides, leading to the formation of biaryl or polyaryl compounds.
Reductive elimination: In metal-catalyzed reactions, the carbon-iodine bond can undergo reductive elimination, leading to the formation of aryl-aryl bonds or other coupling products.
Halogenation reactions: The pyridine ring in 2-chloro-5-iodopyridine can undergo further halogenation reactions under appropriate conditions, leading to the introduction of additional halogen substituents.
Functional group transformations: The presence of both chlorine and iodine substituents allows for various functional group transformations, such as oxidation, reduction, or substitution reactions, depending on the reaction conditions and reagents used.
Arylation reactions: The iodine atom can participate in transition-metal-catalyzed arylation reactions, where it acts as an arylating agent to introduce aryl groups onto other aromatic systems.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
click to sign in and save
2-Chloro-3-fluoro-5-iodoisonicotinic acid
click to sign in and save
2-Chloro-5-iodo-3-(trifluoromethyl)pyridine
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :