Home Chemistry Organic Building Blocks Sulfones 1-(Phenylsulfonyl)-1H-1,2,4-Triazole
Reduction: The triazole ring or the sulfonyl group may undergo reduction reactions. Common reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4) can be used to reduce the compound, depending on the specific site of interest.
Acylation: The triazole ring or the sulfonyl group can be acylated using acylating agents. For example, acyl chlorides or anhydrides could be used to introduce acyl groups onto the triazole or the sulfonyl group.
Halogenation: The compound can undergo halogenation reactions, where halogenating agents like bromine or chlorine can be used to introduce halogen atoms onto the molecule.
Metalation: Under specific conditions, the triazole ring can be metalated, which means a metal atom can be introduced at the triazole nitrogen atoms. This can be achieved using strong bases and appropriate metal sources.
Oxidation: The compound may undergo oxidation reactions under suitable conditions. Oxidizing agents like potassium permanganate (KMnO4) can be used to oxidize various functional groups within the molecule.
Condensation Reactions: 1,2,4-triazole derivatives can participate in condensation reactions, where they react with other compounds to form new products. For example, they can react with aldehydes or ketones to form imine or enamine derivatives.
Ring Closure: Depending on the reaction conditions, the 1,2,4-triazole ring itself may undergo ring closure reactions to form other compounds.
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1-((4-Nitrophenyl)sulfonyl)-1H-1,2,4-triazole
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1-(Mesitylsulfonyl)-3-nitro-1H-1,2,4-triazole
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1-((2,4,6-Triisopropylphenyl)sulfonyl)-1H-1,2,4-triazole
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