Cyclic adenosine monophosphate (cAMP) is an important intracellular messenger, produced by the catalysis of ATP by adenylyl cyclase. It is widely distributed within cells and participates in various biological reactions and signaling pathways, such as metabolic regulation, cell proliferation, neurotransmission, and cardiac function, through the activation of effectors such as protein kinase A (PKA). The regulation of cAMP levels is influenced by various factors, including the action of hormones and neurotransmitters. Abnormalities in the cAMP signaling pathway are associated with various diseases, including cardiovascular diseases, diabetes, and neurodegenerative diseases.