Home Chemistry Heterocyclic Building Blocks Pyridines 2,4-Dibromopyridine
Substitution Reactions: The bromine atoms are susceptible to substitution reactions, where they can be replaced by other functional groups or atoms. For instance, nucleophilic substitution reactions can occur where a nucleophile replaces one or both of the bromine atoms.
Metalation Reactions: The presence of bromine atoms can facilitate metalation reactions, where a metal atom is introduced onto the pyridine ring, typically at the position adjacent to the bromine atoms.
Cross-Coupling Reactions: 2,4-dibromopyridine can participate in cross-coupling reactions, such as Suzuki, Heck, or Stille coupling, where it can be coupled with another organic molecule bearing suitable functional groups under appropriate reaction conditions.
Reduction Reactions: The bromine atoms can be reduced to other functional groups. For example, they can be converted to alkyl or aryl groups through reductive processes.
Electrophilic Aromatic Substitution: The aromatic nature of the pyridine ring makes it susceptible to electrophilic aromatic substitution reactions, where an electrophile replaces one of the hydrogen atoms on the ring.
Oxidation Reactions: The compound can undergo oxidation reactions, where the bromine atoms may be replaced by other functional groups containing oxygen.
Ring Closure Reactions: The presence of bromine atoms can facilitate ring closure reactions, leading to the formation of cyclic compounds under suitable reaction conditions.
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