Home Chemistry Heterocyclic Building Blocks Pyridines Pyridine-2,6-Diamine
Acylation: Pyridine-2,6-diamine can undergo acylation reactions, where an acyl group (-COR) is introduced onto one of its amino groups. This reaction can be useful for synthesizing amides or other derivatives.
Alkylation: Alkylation reactions involve the introduction of alkyl groups onto the amino groups of pyridine-2,6-diamine. This can lead to the formation of alkylated derivatives, which may have different properties compared to the parent compound.
Nitration: Pyridine-2,6-diamine can undergo nitration reactions, where a nitro group (-NO2)is introduced onto the aromatic ring. Nitration can lead to the formation of nitro derivatives, which are important intermediates in the synthesis of various organic compounds.
Reduction: Reduction reactions involve the addition of hydrogen or hydride ions to pyridine-2,6-diamine, leading to the formation of dihydro derivatives. Reductions can be useful for synthesizing saturated analogs or for functional group interconversions.
Oxidation: Oxidation reactions involve the removal of hydrogen atoms or the addition of oxygen atoms to pyridine-2,6-diamine. Oxidation can lead to the formation of oxidized derivatives, which may exhibit different chemical properties compared to the parent compound.
Condensation: Pyridine-2,6-diamine can undergo condensation reactions with carbonyl compounds (such as aldehydes or ketones) to form imine or iminium derivatives. This reaction is commonly used in the synthesis of heterocyclic compounds.
Substitution reactions: Pyridine-2,6-diamine can undergo substitution reactions, where one or more atoms or functional groups on the molecule are replaced by other atoms or groups. Substitution reactions can lead to the formation of various derivatives with different substitution patterns.
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Pyridine-2,3,6-triamine dihydrochloride
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