Chemistry Organic building blocks Ethers (2-chloro-3-methoxyphenyl)boronic acid

(2-chloro-3-methoxyphenyl)boronic acid

These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—OCH3,—B(OH)2).

Reduction: Chlorobenzene can be reduced to form cyclohexane under certain conditions, often using strong reducing agents like sodium in the presence of 【alcohol|https://www.ambeed.com/alcohols.html】.
Wacker Oxidation: Methoxybenzene can undergo the Wacker oxidation using palladium chloride and copper chloride to form the corresponding ketone.
Hydroboration: Phenylboronic acid can undergo hydroboration reactions with 【alkenes|https://www.ambeed.com/alkenyls.html】 or 【alkynes|https://www.ambeed.com/alkynyls.html】, leading to the formation of organoboranes. These can subsequently be transformed into various functional groups.

Further Reading:

Framework+−

(1s,4ar,7ar)-1-(((s)-tetrahydro-2h-pyran-2-yl)oxy)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran (2,2,2-trifluoroethoxy)benzene (2-(benzyloxy)phenyl)boronic acid (2-(phenoxymethyl)phenyl)boronic acid (2-chloro-3-methoxyphenyl)boronic acid (2-chloroethoxy)benzene (2-methoxyethoxy)benzene (3-(benzyloxy)phenyl)boronic acid (3-(phenoxymethyl)phenyl)boronic acid (3-chloro-2-methoxyphenyl)boronic acid (3-phenoxyphenyl)methanol (4-(benzyloxy)phenyl)boronic acid (4-(phenoxymethyl)phenyl)boronic acid (4-methoxyphenyl)(phenyl)methanone (9h-fluoren-9-yl)methyl (2-(benzyloxy)ethyl)carbamate (9h-fluoren-9-yl)methyl (4-methoxybenzyl)carbamate (allyloxy)benzene (ethoxymethyl)benzene (hexyloxy)benzene (methoxymethyl)benzene (prop-2-yn-1-yloxy)benzene (r)-2-phenoxytetrahydro-2h-pyran (s)-7-(((s)-tetrahydro-2h-pyran-2-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione 1,2-bis(benzyloxy)benzene 1,2-dichloro-3-methoxybenzene 1,2-dichloro-4-methoxybenzene 1,2-difluoro-3-methoxybenzene 1,2-difluoro-4-methoxybenzene 1,2-dimethoxybenzene 1,2-diphenoxyethane 1,3-bis(benzyloxy)benzene 1,3-dibromo-2-methoxybenzene 1,3-dichloro-2-methoxybenzene 1,3-diiodo-2-phenoxybenzene 1,3-dimethoxybenzene 1,3-diphenoxybenzene 1,4-dichloro-2-methoxybenzene 1,4-dimethoxybenzene 1-(2-methoxyphenyl)ethan-1-one 1-(3-(benzyloxy)phenyl)ethan-1-one 1-(3-methoxyphenyl)ethan-1-one 1-(3-methoxyphenyl)piperazine 1-(4-(benzyloxy)phenyl)ethan-1-one 1-(4-methoxybenzyl)-1h-pyrazole 1-(benzyloxy)-2-bromobenzene 1-(benzyloxy)-2-chlorobenzene 1-(benzyloxy)-2-fluorobenzene 1-(benzyloxy)-2-methoxybenzene 1-(benzyloxy)-2-methylbenzene 1-(benzyloxy)-2-nitrobenzene 1-(benzyloxy)-3-bromobenzene 1-(benzyloxy)-3-chlorobenzene 1-(benzyloxy)-3-fluorobenzene 1-(benzyloxy)-3-methylbenzene 1-(benzyloxy)-3-nitrobenzene 1-(benzyloxy)-4-bromobenzene 1-(benzyloxy)-4-iodobenzene 1-(bromomethyl)-2-methoxybenzene 1-(bromomethyl)-3-methoxybenzene 1-(difluoromethoxy)-2-fluorobenzene 1-benzyl-4-methoxybenzene 1-bromo-2,3-dimethoxybenzene 1-bromo-2-chloro-3-methoxybenzene 1-bromo-2-ethoxybenzene 1-bromo-2-fluoro-3-methoxybenzene 1-bromo-2-phenoxybenzene 1-bromo-3-methoxybenzene 1-bromo-3-phenoxybenzene 1-bromo-4-phenoxybenzene 1-chloro-2,4-dimethoxybenzene 1-chloro-2-ethoxybenzene 1-chloro-2-phenoxybenzene 1-chloro-2-propoxybenzene 1-chloro-3-fluoro-2-methoxybenzene 1-chloro-3-methoxybenzene 1-chloro-3-phenoxybenzene 1-chloro-4-methoxybenzene 1-chloro-4-phenoxybenzene 1-cyclopropyl-3-(4-(quinolin-4-yloxy)phenyl)urea 1-ethoxy-2,3-difluorobenzene 1-ethoxy-2-fluorobenzene 1-ethoxy-3-nitrobenzene 1-fluoro-2-(trifluoromethoxy)benzene 1-fluoro-2-isopropoxybenzene 1-fluoro-2-phenoxybenzene 1-fluoro-3-methoxybenzene 1-fluoro-3-phenoxybenzene 1-fluoro-4-(trifluoromethoxy)benzene 1-fluoro-4-methoxybenzene 1-fluoro-4-phenoxybenzene 1-iodo-2-methoxybenzene 1-iodo-3-methoxybenzene 1-iodo-4-methoxybenzene 1-iodo-4-phenoxybenzene 1-methoxy-2-(trifluoromethyl)benzene 1-methoxy-3-(trifluoromethoxy)benzene 1-methoxy-3-(trifluoromethyl)benzene 1-methoxy-3-nitrobenzene 1-methoxy-4-(phenoxymethyl)benzene 1-methoxy-4-(trifluoromethyl)benzene 1-methoxy-4-nitrobenzene 1-methoxynaphthalene 1-methyl-3-phenoxybenzene 1-nitro-2-phenoxybenzene 1-nitro-4-phenoxybenzene 1-phenoxy-3-(trifluoromethyl)benzene 1-phenoxy-4-(trifluoromethyl)benzene 1-phenyl-3-(4-(pyridin-4-yloxy)phenyl)urea 2,3,5,6,8,9,11,12-octahydrobenzo[b][1,4,7,10,13]pentaoxacyclopentadecine 2,3-dimethoxypyridine 2,4,6-triphenoxy-1,3,5-triazine 2,4-dibromo-1-methoxybenzene 2,4-dichloro-1-methoxybenzene 2,4-difluoro-1-methoxybenzene 2,4-dimethoxy-1-nitrobenzene 2,4-dimethoxypyrimidine 2,6-dimethoxypyridine 2-(2-methoxyphenyl)acetic acid 2-(3-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(3-methoxyphenyl)acetic acid 2-(4-(benzyloxy)phenyl)acetonitrile 2-(4-methoxyphenyl)acetic acid 2-(benzyloxy)benzaldehyde 2-(benzyloxy)naphthalene 2-(benzyloxy)phenol 2-(methoxymethyl)morpholine 2-(methoxymethyl)pyrrolidine 2-(phenoxymethyl)oxirane 2-(phenoxymethyl)pyridine 2-(phenoxymethyl)tetrahydro-2h-pyran 2-bromo-1,3-dimethoxybenzene 2-bromo-1,4-dimethoxybenzene 2-bromo-1-fluoro-4-methoxybenzene 2-bromo-1-methoxy-3-methylbenzene 2-bromo-1-methoxy-4-methylbenzene 2-bromo-3-methoxypyrazine 2-bromo-4-methoxy-1-nitrobenzene 2-bromo-4-methoxyaniline 2-bromo-4-methoxybenzaldehyde 2-bromo-4-methoxybenzoic acid 2-bromo-5-methoxybenzaldehyde 2-bromo-6-methoxyaniline 2-bromo-6-methoxyphenol 2-chloro-1,3-dimethoxybenzene 2-chloro-1,4-dimethoxybenzene 2-chloro-3-methoxybenzaldehyde 2-chloro-3-methoxybenzoic acid 2-chloro-4-fluoro-1-methoxybenzene 2-chloro-4-methoxypyrimidine 2-chloro-5-methoxyaniline 2-chloro-6-methoxyaniline 2-chloro-6-methoxyphenol 2-ethoxynaphthalene 2-ethoxypyridine 2-ethoxypyrimidine 2-fluoro-1,3-dimethoxybenzene 2-fluoro-1-methoxy-4-nitrobenzene 2-fluoro-4-methoxyaniline 2-fluoro-5-methoxybenzoic acid 2-fluoro-5-methoxypyridine 2-fluoro-6-methoxypyridine 2-isopropoxypyridine 2-methoxy-1,1'-biphenyl 2-methoxy-1,3,5-triazine 2-methoxy-4-methylpyridine 2-methoxy-5-methylpyridine 2-methoxy-6-methylpyridine 2-methoxy-6-nitrophenol 2-methoxybenzamide 2-methoxybenzenesulfonyl chloride 2-methoxynaphthalene 2-methoxyphenol 2-methoxypyrazine 2-methoxypyridine 2-methoxypyrimidin-4-amine 2-methoxypyrimidine 2-methoxythiophene 2-methyl-n-phenylaniline 2-phenoxyacetonitrile 2-phenoxyaniline 2-phenoxybenzonitrile 2-phenoxyethan-1-ol 2-phenoxypropanoic acid 2-phenoxypyrimidine 2-phenoxytetrahydro-2h-pyran 2-phenoxythiazole 2-propoxypyridine 3,5-dimethoxypyridine 3-(3-methoxyphenyl)propanoic acid 3-(benzyloxy)aniline 3-(benzyloxy)benzaldehyde 3-(benzyloxy)benzoic acid 3-(benzyloxy)phenol 3-(methoxymethyl)morpholine 3-chloro-2-methoxybenzoic acid 3-chloro-4-methoxyaniline 3-chloro-4-methoxybenzaldehyde 3-chloro-4-methoxybenzoic acid 3-ethoxypyridine 3-fluoro-2-methoxypyridine 3-fluoro-4-methoxybenzoic acid 3-methoxypiperidine 3-methoxypyridazine 3-methoxypyridine 3-methoxythiophene 3-phenoxyaniline 3-phenoxybenzaldehyde 3-phenoxybenzoic acid 3-phenoxybenzonitrile 3-phenoxypropanoic acid 3-phenoxypyrrolidine 4-(3-phenoxypropyl)morpholine 4-(benzyloxy)aniline 4-(benzyloxy)benzaldehyde 4-(benzyloxy)benzoic acid 4-(benzyloxy)phenol 4-(difluoromethoxy)aniline 4-(dimethoxymethyl)pyrimidine 4-(phenylethynyl)phenol 4-chloro-2-methoxypyrimidine 4-chloro-5-methoxypyrimidine 4-chloro-6-methoxypyrimidine 4-ethoxypyridine 4-ethoxypyrimidine 4-methoxy-1,1'-biphenyl 4-methoxy-1h-indazole 4-methoxy-1h-indole 4-methoxy-2-methylpyrimidine 4-methoxy-n-phenylaniline 4-methoxy-n-phenylbenzenesulfonamide 4-methoxybenzenesulfonamide 4-methoxypyridazine 4-methoxypyridine 4-methoxypyrimidin-2-amine 4-methoxypyrimidine 4-phenoxyaniline 4-phenoxybenzaldehyde 4-phenoxybenzoic acid 4-phenoxypyridine 4-phenoxypyrimidine 4-phenoxyquinoline 4-phenoxytetrahydro-2h-pyran 5-(benzyloxy)pyrimidine 5-fluoro-2-methoxypyridine 5-methoxy-1h-benzo[d]imidazole 5-methoxy-1h-indazole 5-methoxy-1h-indole 5-methoxy-2-methyl-1h-indole 5-methoxy-2-nitroaniline 5-methoxyindoline 5-methoxyisobenzofuran-1(3h)-one 5-methoxyisoquinoline 6-methoxy-1,2,3,4-tetrahydroisoquinoline 6-methoxy-1h-indazole 6-methoxy-1h-indole 6-methoxy-1h-pyrrolo[2,3-b]pyridine 6-methoxy-3,4-dihydroisoquinolin-1(2h)-one 6-methoxybenzo[d]thiazole 6-methoxybenzofuran 6-methoxychromane 6-methoxyisoindolin-1-one 6-methoxyquinoxaline 7-(benzyloxy)quinoline 7-methoxy-1,2,3,4-tetrahydroisoquinoline 7-methoxy-1h-indazole 7-methoxy-1h-indole 7-methoxy-3,4-dihydroquinolin-2(1h)-one 7-methoxyisoquinoline 8-methoxyisoquinoline 8-methoxyquinazoline Butoxybenzene Ethoxybenzene Ethyl 2-phenoxyacetate Isobutoxybenzene Isopropoxybenzene Methoxycyclohexane Methyl 2-methoxybenzoate Methyl 2-phenoxyacetate Methyl 2-phenoxybenzoate Methyl 3-(benzyloxy)benzoate Methyl 3-methoxybenzoate Methyl 4-phenoxybenzoate N,n-dimethyl-2-phenoxyethan-1-amine N-(2-phenoxyphenyl)methanesulfonamide N-(4-phenoxyphenyl)acetamide N-phenyl-n-(4-(quinolin-4-yloxy)phenyl)cyclopropane-1,1-dicarboxamide Phenethoxybenzene Propoxybenzene Tert-butoxybenzene Tert-butyl 3-methoxypyrrolidine-1-carboxylate Tert-butyl 4-phenoxypiperidine-1-carboxylate Tert-butyl 5-methoxy-1h-indole-1-carboxylate

By Key Group+−

(2-ethylhexyl)oxy (s)-2-methoxyethanamine (trimethylsilyl)ethoxy 2,2,2-trifluoroethoxy 2,2-difluoroethoxy 2,2-dimethoxyethyl 2-bromo-1,1,2,2-tetrafluoroethoxy 2-bromoethoxy 2-methoxyethoxy 2-methoxyethoxymethyl 2-methoxyethyl 2-methyl-2-oxypropanoic acid 2-oxoacetic acid 2-oxy-propanoic acid 3-(oxy)propanoic acid 3-methoxypropoxy 4-bromobutoxy Allyloxy Benzo-crown-ether Butoxy Butoxy-phenyl-boronic acid Butoxy-phenyl-boronic acid/ester Butoxy-phenyl-boronic-acid Chloroanisole Cyanomethoxy Decyloxy Diethoxy Diethoxy Diethoxyethyl Diethoxyethyl Diethoxymethyl Diethoxymethyl Diethylaminoethoxy Dimethoxyethyl Dimethoxymethyl Dimethoxypropane Dimethoxypropane Dimethylamino ethoxy Dimethylaminopropoxy Dioxane Dioxepine Dioxepine Dioxopropan Dioxopropan Disulfide Dodecyloxy Ethoxyethanol Ethyl 2-oxyacetate Fluoromethoxy-nitro-benzene Heptyloxy Hexyloxy Isobutoxy Isopentyloxy Isopropoxy Isopropoxyphenylboronic Methoxy-acetic acid Methoxy-benzoimidazole Methoxy-carbazole Methoxy-chromen-one Methoxy-indanone Methoxy-indazole-carboxylate Methoxy-inden-amine Methoxy-indole-carboxylate Methoxy-methyl-indole Methoxy-methylbenzene Methoxy-naphthyridine Methoxy-pyran Methoxy-pyrazolo-pyridine Methoxy-trifluoromethyl-benzene Methoxyacetate Methoxychroman Methoxyethoxyethoxyethoxy Methoxyphenylboronic-acid Methyl 2-oxy-acetate Nitroanisole Octyloxy Oxy ethanamine Oxy-acetohydrazide Oxyacetic acid Oxypropane-1,2-dio Prop-2-yn-1-oxy Propoxy Tert-butoxy Tert-butoxybromobenzene Tert-butoxymethyl Tetrahydroquinoline-methoxy

By Parent Nucleus+−

Aliphatic heterocycles Aromatic heterocycles Azetidines Benzimidazoles Benzofurans Benzothiazoles Benzothiophenes Benzoxazoles Carbazoles Dioxolanes Epoxides Furans Guanidines Imidazoles Imidazolines Indazoles Indoles Indolines Isoquinolines Isoxazoles Morpholines Naphthyridines Non-halogenated heterocycles Other aliphatic heterocycles Other aromatic heterocycles Oxadiazoles Oxazoles Oxazolidines Oxetanes Piperazines Piperidines Purines Pyrans Pyrazines Pyrazoles Pyridazines Pyridines Pyrimidines Pyrroles Pyrrolidines Pyrrolines Quinazolines Quinolines Quinoxalines Quinuclidines Spiroes Tetrahydrofurans Tetrahydroisoquinolines Tetrahydropyrans Tetrahydroquinolines Thiadiazoles Thiazoles Thiazolidines Thiophenols Triazines Triazoles

By Functional Group+−

acyl chlorides alcohols aldehydes aliphatic chain hydrocarbons aliphatic cyclic hydrocarbons alkenyls alkyls alkynyls Amides amidines Amines anhydrides Aryls benzyl bromides benzyl chlorides Bromides carboxylic acid salts carboxylic acids Chiral building blocks Chlorides difluoromethyls Esters Fluorinated building blocks hydrazides hydrazines hydrazones hydroxylamines iodides isocyanates and isothiocyanates ketones nitrates and nitrites nitriles nitroes phenols phosphoruses sulfamides sulfides sulfonates sulfones sulfonic acids sulfonyl chlorides sulfoxides thioesters thiols Thiophenes thioureas trifluoromethyls ureas

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    (2,6-Dichloro-3-methoxyphenyl)boronic acid

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    (2,6-Dichloro-3-methoxyphenyl)boronic acid

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    (2-Chloro-3-methoxyphenyl)boronic acid

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    (2-Chloro-3-methoxyphenyl)boronic acid

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    (2-Chloro-4-fluoro-3-methoxyphenyl)boronic acid

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    (2-Chloro-4-fluoro-3-methoxyphenyl)boronic acid

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    2-Chloro-6-fluoro-3-methoxyphenylboronic acid

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    2-Chloro-6-fluoro-3-methoxyphenylboronic acid

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    (6-Bromo-2-chloro-3-methoxyphenyl)boronic acid

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    (6-Bromo-2-chloro-3-methoxyphenyl)boronic acid

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