Home Chemistry Heterocyclic Building Blocks Pyridines 3-Fluoropyridin-2-Amine
Substitution Reactions: The fluorine atom can be substituted with other functional groups such as alkyl, acyl, or aryl groups through nucleophilic aromatic substitution (SNAr) reactions.
Acylation Reactions: The amine group can undergo acylation reactions with acyl chlorides or acid anhydrides to form amides.
Alkylation or Arylation Reactions: The amino group can be alkylated or arylated using appropriate alkyl halides or aryl halides under suitable conditions.
Reductive Amination: The amine group can undergo reductive amination with carbonyl compounds (aldehydes or ketones) to form secondary or tertiary amines.
Cyclization Reactions: The amine group and the adjacent fluorine-substituted carbon can participate in cyclization reactions to form heterocyclic compounds.
Oxidation Reactions: The amine group can be oxidized to form amine oxides or other oxidized derivatives.
Condensation Reactions: The amine group can undergo condensation reactions with carbonyl compounds to form imines or Schiff bases.
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3-Fluoro-4-(trifluoromethyl)pyridin-2-amine
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3-Fluoro-5-(trifluoromethyl)pyridin-2-amine
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