Home Chemistry Organic Building Blocks Hydrazones 1-Benzylidene-2-Phenylhydrazine
Schiff Base Formation: The compound can react with aldehydes and ketones to form Schiff bases. In this reaction, the nitrogen atom of the hydrazone group can react with the carbonyl group of the aldehyde or ketone to form a carbon-nitrogen double bond (imine or Schiff base). This reaction can be used in organic synthesis for the formation of C=N bonds.
Azo Coupling: If the hydrazone group is diazotized, it can undergo azo coupling reactions with aromatic amines to form azo compounds. This reaction is often used in the synthesis of azo dyes.
Acid-Catalyzed Hydrolysis: Under acidic conditions, the hydrazone group can undergo hydrolysis, leading to the cleavage of the C=N bond and the formation of primary amines.
Base-Catalyzed Hydrolysis: Under basic conditions, the hydrazone group can undergo hydrolysis, leading to the formation of carboxylic acids and primary amines.
Grignard Reactions: The compound can react with Grignard reagents (organomagnesium compounds) to form new carbon-carbon bonds.
Nucleophilic Addition Reactions: The carbon-nitrogen double bond in the hydrazone group can undergo nucleophilic addition reactions with nucleophiles such as alkoxides or primary amines.
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