Home Chemistry Organic Building Blocks Bromides 1,2-Dibromo-4-Fluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—F).
Electrophilic Aromatic Substitution (EAS): Bromobenzene can react with electrophiles in substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts acylation/alkylation.
Fluorine Substitution: Fluorobenzene can undergo further substitution reactions to replace the fluorine atom with other functional groups. This can be achieved through nucleophilic aromatic substitution reactions. The electron-withdrawing nature of fluorine can affect the regioselectivity and reactivity of such substitutions.
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1,2-Dibromo-5-fluoro-3-(trifluoromethyl)benzene
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2,3-Dibromo-1-chloro-5-fluoro-4-methylbenzene
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