Home Chemistry Organic Building Blocks Chlorides 1-Chloro-2-Isocyanatobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—N=C=O).
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
Nucleophilic Substitution: The isocyanate group can undergo nucleophilic substitution reactions with nucleophiles, such as 【amines|https://www.ambeed.com/amines.html】, 【alcohols|https://www.ambeed.com/alcohols.html】, or 【thiols|https://www.ambeed.com/thiols.html】, leading to the formation of 【urea|https://www.ambeed.com/ureas.html】, carbamate, or thiocarbamate derivatives, respectively.
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1-Chloro-2-isocyanato-4-(trifluoromethyl)benzene
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2,4-Dichloro-3-isocyanato-1,5-dimethoxybenzene
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2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene
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