Home Chemistry Heterocyclic Building Blocks Pyridines 3,5-Diphenylpyridine
Electrophilic Aromatic Substitution: 3,5-diphenylpyridine, like other aromatic compounds, can undergo electrophilic aromatic substitution reactions. For example, you can nitrate it using concentrated nitric acid and sulfuric acid to produce 3,5-dinitrophenylpyridine.
Reduction: The phenyl groups in 3,5-diphenylpyridine can be reduced using reagents like lithium aluminum hydride (LiAlH4) to form 3,5-diphenylpyridine.
Sulfonation: 3,5-diphenylpyridine can be sulfonated by reacting it with sulfuric acid to introduce a sulfonic acid group, making it more water-soluble and potentially reactive in other ways.
Cross-Coupling Reactions: You can perform cross-coupling reactions with 3,5-diphenylpyridine using various coupling partners like aryl halides, boronic acids, or Suzuki-Miyaura reactions to synthesize more complex molecules.
Arylation: Using palladium-catalyzed reactions, you can introduce additional aryl groups to the pyridine ring, expanding the molecule's structure.
Friedel-Crafts Acylation: 3,5-diphenylpyridine can undergo acylation reactions when treated with acyl halides in the presence of a Lewis acid catalyst.
Oxidation: You can oxidize 3,5-diphenylpyridine to introduce various functional groups, depending on the oxidizing agent used.
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5,5'-(Pyridine-3,5-diyl)diisophthalic acid
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