Home Chemistry Organic Building Blocks Sulfones 2-(Methylsulfonyl)Aniline
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —SO2CH3,—NH2).
Aromatic Substitution: Like other aromatic compounds, (methylsulfonyl)benzene can undergo electrophilic aromatic substitution reactions. For example, it can react with strong electrophiles such as nitronium ions (NO2+) to introduce substituents onto the benzene ring. The sulfonyl group is generally not directly involved in these reactions.
Reimer-Tiemann Reaction: Aniline can react with chloroform (CHCl3) and a base to undergo the Reimer-Tiemann reaction, leading to the formation of a salicylaldehyde derivative.
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2-(Methylsulfonyl)-5-(trifluoromethyl)aniline
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