Home Chemistry Organic Building Blocks Bromides 2-Bromo-4-Chloro-1-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—NO2,—Cl).
Electrophilic Aromatic Substitution (EAS): Bromobenzene can react with electrophiles in substitution reactions, such as nitration, sulfonation, halogenation, and Friedel-Crafts acylation/alkylation.
Halogenation: Nitrobenzene can undergo halogenation reactions, where halogen atoms (such as chlorine or bromine) are substituted onto the benzene ring. This is usually achieved using halogenating agents in the presence of a catalyst.
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
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1-Bromo-5-chloro-3-fluoro-2-nitrobenzene
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