SMARC (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin) proteins are involved in chromatin remodeling, belonging to the SWI/SNF protein family. Members of this family regulate gene expression by remodeling chromatin structure. SMARC proteins comprise multiple subunits, each playing a specific role in the chromatin remodeling process. These proteins are localized in the nucleus and participate in various signaling pathways, affecting biological processes such as cell division, differentiation, and development. Specific expression of SMARC genes is essential for maintaining normal cell functions, and mutations can lead to diseases like cancer.