Chemistry Heterocyclic building blocks Pyrazoles 1-cyclopropyl-1h-pyrazole

1-cyclopropyl-1h-pyrazole

Acylation: The pyrazole nitrogen atoms can be acylated by reacting with acyl chlorides or anhydrides in the presence of a base to form N-acyl derivatives. Alkylation: You can alkylate the pyrazole ring by using alkyl halides or alkylating agents under suitable conditions. This leads to the introduction of alkyl groups on the pyrazole nitrogen atoms. Ring Opening: The cyclopropyl ring can be opened under certain conditions, leading to the formation of a linear compound. Cyclization Reactions: 1-Cyclopropyl-1H-pyrazole can participate in cyclization reactions to form various fused ring systems, depending on the reaction conditions and reagents. Reduction: The cyclopropyl group can be reduced to a cyclopropylmethyl group using reducing agents such as lithium aluminum hydride (LiAlH4) or hydrogen gas H2 with a suitable catalyst. Oxidation: Oxidation reactions can be employed to convert the cyclopropyl group into other functional groups. Metalation: The pyrazole ring can undergo metalation reactions, where a metal atom or group replaces a hydrogen atom on the ring. This can serve as a key step in various synthetic pathways. Condensation Reactions: 1-Cyclopropyl-1H-pyrazole can participate in condensation reactions to form heterocyclic compounds or other products.

Further Reading:

Framework+−

(1-methyl-1h-pyrazol-3-yl)methanol (1-phenyl-1h-pyrazol-4-yl)boronic acid 1,3-dimethyl-1h-pyrazole 1,3-diphenyl-1h-pyrazole 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 1,5-diphenyl-1h-pyrazole 1-(2-chlorophenyl)-1h-pyrazole 1-(3-chlorophenyl)-1h-pyrazole 1-(4-methoxybenzyl)-1h-pyrazole 1-(azetidin-3-yl)-1h-pyrazole 1-(tetrahydro-2h-pyran-2-yl)-1h-pyrazole 1-(tetrahydro-2h-pyran-4-yl)-1h-pyrazole 1-benzyl-1h-pyrazolo[3,4-b]pyridine 1-benzyl-4-bromo-1h-pyrazole 1-benzyl-4-iodo-1h-pyrazole 1-cyclopentyl-1h-pyrazole 1-cyclopropyl-1h-pyrazole 1-methyl-1h-pyrazol-3-amine 1-methyl-3-phenyl-1h-pyrazole 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazole 1-methyl-5-phenyl-1h-pyrazole 1-phenyl-1h-pyrazol-3-amine 1-phenyl-1h-pyrazol-3-ol 1-phenyl-1h-pyrazol-5-amine 1-phenyl-1h-pyrazole-3-carboxylic acid 1-phenyl-1h-pyrazole-4-carbaldehyde 1-phenyl-1h-pyrazole-4-carbonitrile 1-phenyl-1h-pyrazole-4-carboxylic acid 1-phenyl-1h-pyrazole-5-carboxylic acid 1-phenyl-3-(trifluoromethyl)-1h-pyrazole 1-trityl-1h-pyrazole 1h-pyrazol-4-amine 1h-pyrazol-4-ol 1h-pyrazol-5-amine 1h-pyrazole-4-carbaldehyde 1h-pyrazole-4-carbonitrile 1h-pyrazole-4-carboxylic acid 1h-pyrazole-4-sulfonyl chloride 1h-pyrazole-5-carboxamide 1h-pyrazole-5-carboxylic acid 1h-pyrazolo[3,4-b]pyrazine 1h-pyrazolo[3,4-b]pyridin-5-amine 1h-pyrazolo[3,4-d]pyrimidin-4-amine 1h-pyrazolo[4,3-d]pyrimidine 2,3-dihydropyrazolo[5,1-b]oxazole 2,4-dihydro-3h-pyrazol-3-one 2,6-di(1h-pyrazol-1-yl)pyridine 2-(1h-pyrazol-1-yl)pyridine 2-(1h-pyrazol-1-yl)pyrimidine 2-(1h-pyrazol-3-yl)pyridine 2-phenyl-2,4-dihydro-3h-pyrazol-3-one 3-(tert-butyl)-1-phenyl-1h-pyrazole 3-bromo-1-methyl-1h-pyrazole 3-bromopyrazolo[1,5-a]pyridine 3-bromopyrazolo[1,5-a]pyrimidine 3-chloro-1-methyl-1h-pyrazole 3-cyclopropyl-1h-pyrazole 3-iodo-1-methyl-1h-pyrazole 3-iodo-1h-pyrazolo[3,4-b]pyridine 3-methyl-1-phenyl-1h-pyrazole 3-phenyl-1h-pyrazol-5-amine 4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c]pyridine 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridine 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine 4-(1h-pyrazol-1-yl)benzoic acid 4-(1h-pyrazol-1-yl)piperidine 4-bromo-1-methyl-1h-pyrazole 4-bromo-1-phenyl-1h-pyrazole 4-bromo-1h-pyrazolo[3,4-b]pyridine 4-bromopyrazolo[1,5-a]pyridine 4-chloro-1h-pyrazole 4-chloro-1h-pyrazolo[3,4-b]pyridine 4-chloro-1h-pyrazolo[3,4-d]pyrimidine 4-iodo-1h-pyrazole 4-methyl-1-phenyl-1h-pyrazole 4-methyl-1h-pyrazole 4-nitro-1h-pyrazole 4-phenyl-1h-pyrazole 5,6-dihydro-4h-pyrrolo[1,2-b]pyrazole 5-(difluoromethyl)-1h-pyrazole 5-bromo-1h-pyrazole 5-bromo-1h-pyrazolo[3,4-b]pyridine 5-bromo-1h-pyrazolo[3,4-c]pyridine 5-chloro-1h-pyrazole 5-chloro-1h-pyrazolo[3,4-b]pyridine 5-chloropyrazolo[1,5-a]pyrimidine 5-cyclopropyl-1h-pyrazole 5-iodo-1h-pyrazole 5-nitro-1h-pyrazole 5-nitro-1h-pyrazolo[3,4-b]pyridine 5-phenyl-1h-pyrazole-3-carboxylic acid 6,7-dihydro-5h-pyrazolo[5,1-b][1,3]oxazine 6-bromopyrazolo[1,5-a]pyridine 6-bromopyrazolo[1,5-a]pyrimidine 6-chloro-1h-pyrazolo[3,4-d]pyrimidine 7-chloropyrazolo[1,5-a]pyrimidine Ethyl 1-phenyl-1h-pyrazole-3-carboxylate Ethyl 1-phenyl-1h-pyrazole-4-carboxylate Ethyl 1h-pyrazole-4-carboxylate Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate Ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate Methyl 1h-pyrazole-4-carboxylate Methyl 1h-pyrazolo[3,4-b]pyridine-5-carboxylate Methyl pyrazolo[1,5-a]pyridine-3-carboxylate Pyrazolo[1,5-a]pyrazine Pyrazolo[1,5-a]pyridine-2-carboxylic acid Pyrazolo[1,5-a]pyridine-3-carboxylic acid Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid Tert-butyl 1h-pyrazolo[3,4-b]pyridine-1-carboxylate Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazole-1-carboxylate

By Key Group+−

Amino-pyrazole-carboxylate Amino-pyrazolopyridine Aminopyrazolo Benzylpyrazol-amide Bipyrazole Bromo-methyl-pyrazole Bromo-pyrazol-amide Bromo-pyrazole-carboxylate Bromo-pyrazolopyridine Bromo-pyrazolopyrimidine Bromo-trifluoromethyl-pyrazole Bromopyrazolo Chloro-methyl-pyrazole Chloro-pyrazolamide Chloro-pyrazole Chloro-pyrazole-carboxylate Chloro-pyrazolopyridine Chloro-pyrazolopyrimidine Chloropyrazolo Dichloropyrazolo Difluoromethyl-pyrazole Difluoromethyl-pyrazole-carboxylate Dihydropyrazolo Dimethyl-pyrazol-amide Dimethyl-pyrazole-carboxylate Dimethyl-pyrazole-carboxylic acid Dimethylpyrazole Dimethylpyrazolo Dioxaborolan-pyrazole Ethyl-pyrazol-amide Ethylpyrazole Fluoropyrazolo Hydroxy-pyrazole Hydroxy-pyrazolopyrimidine Hydroxypyrazolo Iodo-methyl-pyrazole Iodo-pyrazole-carboxylate Iodopyrazolo Isopropyl-pyrazol-amide Methoxy-pyrazolo-pyridine Methoxypyrazolo Methy-pyrazolooxazine Methyl-hydrox-ypyrazole Methyl-nitro-pyrazole Methyl-pyrazol-one Methyl-pyrazole-carboxylic acid Methyl-pyrazole-carboxylic-acid Methyl-pyrazolone Methyl-pyrazolopyridine Methylpyrazole Methylpyrazolo Nitro-pyrazole-carboxylate Phenyl-pyrazol-amide Phenyl-pyrazole-carboxylate Phenyl-pyrazolidine Phenylpyrazole Pyrazo-morpholine Pyrazol-amine Pyrazol-boronic acid Pyrazol-methanol Pyrazol-one Pyrazol-piperazine Pyrazol-pyridine Pyrazole-carbonitrile Pyrazole-carboxylate Pyrazole-carboxylic acid Pyrazole-ethanol Pyrazole-hydrochloride Pyrazole-methamine Pyrazole-phenyl-boronic-acid Pyrazole-piperidine Pyrazolo-pyrimidine Pyrazolooxazine Pyrazolopyrazine Pyrazolopyridin-ol Pyrazolopyridin-one Pyrazolopyridine Pyrazolopyridine-carbonitrile Pyrazolopyridine-carboxylate Pyrazolopyridine-carboxylic acid Pyrazolopyridine-carboxylic-acid Pyrazolopyridine-methanol Pyrazolopyrimid-one Pyrazolopyrimidine Pyrazolotriazine Pyridine-pyrazole Pyrimidine-pyrazole Pyrrolopyrazole Tetrahydropyran-pyrazole Tetrahydropyranopyrazole Tetrahydropyrazolo Trifluoromethyl-phenyl-pyrazol Trifluoromethyl-pyrazol-amide Trifluoromethyl-pyrazole Trifluoromethyl-pyrazolone

By Parent Nucleus+−

aliphatic heterocycles aromatic heterocycles azetidines furans guanidines imidazoles indazoles indoles other aliphatic heterocycles other aromatic heterocycles oxetanes piperazines Piperidines pyrazines pyridazines Pyridines Pyrimidines pyrroles pyrrolidines quinolines tetrahydrofurans tetrahydropyrans thiophenes

By Functional Group+−

alcohols aldehydes aliphatic chain hydrocarbons aliphatic cyclic hydrocarbons alkenyls alkyls alkynyls amides amines aryls benzyl bromides benzyl chlorides bromides carboxylic acids Chiral building blocks chlorides difluoromethyls esters ethers fluorinated building blocks hydrazones iodides ketones nitriles nitroes oximes phenols phosphoruses sulfamides sulfides sulfonates sulfonic acids sulfonyl chlorides trifluoromethyls ureas

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    Typically In Stock
    Purity
    • Please Select
    • 99+%
    • 99%
    • 98+%
    • 98%
    • 97+%
    • 97%
    • 96+%
    • 96%
    • 95+%
    • 95%
    • 93%
    • 90+%
    • 90%
    Size
    • Please Select
    • 1mg
    • 2mg
    • 5mg
    • 10mg
    • 25mg
    • 50mg
    • 100mg
    • 250mg
    • 1g
    • 5g
    • 10g
    • 25g
    • 100g
    • 500g
    • 1000g
    • 1kg
    Clear Filters
    1-(Cyclopropyl)-1H-pyrazole-4-carbaldehyde

    click to sign in and save

    A1261721082066-00-997%

    1-(Cyclopropyl)-1H-pyrazole-4-carbaldehyde

    $18.00/100mg

    Detail
    1-Cyclopropyl-4-nitro-1H-pyrazole

    click to sign in and save

    A5495921240568-16-497%

    1-Cyclopropyl-4-nitro-1H-pyrazole

    $56.00/250mg

    Detail
    1-Cyclopropyl-1H-pyrazole-4-carboxylic acid

    click to sign in and save

    A2328461622883-44-697%

    1-Cyclopropyl-1H-pyrazole-4-carboxylic acid

    $43.00/100mg

    Detail
    1-Cyclopropyl-1H-pyrazole-3-carboxylic acid

    click to sign in and save

    A2753171403333-94-798%

    1-Cyclopropyl-1H-pyrazole-3-carboxylic acid

    $1303.00/5g

    Detail
    4-Bromo-1-cyclopropyl-1H-pyrazole

    click to sign in and save

    A1037011151802-23-195%

    4-Bromo-1-cyclopropyl-1H-pyrazole

    $110.00/10g

    Detail
    1-Cyclopropyl-1H-pyrazole

    click to sign in and save

    A1820161151814-36-695%

    1-Cyclopropyl-1H-pyrazole

    $990.00/5g

    Detail
    1-Cyclopropyl-4-iodo-1H-pyrazole

    click to sign in and save

    A1818291239363-40-696%

    1-Cyclopropyl-4-iodo-1H-pyrazole

    $33.00/250mg

    Detail
    1-Cyclopropyl-1H-pyrazol-3-amine

    click to sign in and save

    A5043721240565-06-398%

    1-Cyclopropyl-1H-pyrazol-3-amine

    $31.00/50mg

    Detail
    1    page 1 of 1 Pages

    Inquiry