Home Chemistry Heterocyclic Building Blocks Pyridines 5-Bromopicolinic Acid
Substitution Reactions: Being a halogenated compound, 5-bromopicolinic acid can undergo substitution reactions where the bromine atom is replaced with other functional groups or leaving groups. For example, it can undergo nucleophilic substitution reactions with nucleophiles like amines or alcohols.
Esterification: 5-Bromopicolinic acid can react with alcohols in the presence of an acid catalyst to form esters. This reaction is known as esterification and is commonly used to prepare esters of carboxylic acids.
Amidation: Under appropriate conditions, 5-bromopicolinic acid can undergo amidation reactions to form amides. This reaction involves the substitution of the hydroxyl group of the carboxylic acid with an amino group.
Decarboxylation: carboxylic acids can undergo decarboxylation reactions under certain conditions, typically involving heating. This reaction results in the removal of the carboxyl group (-COOH) from the molecule, often yielding substituted aromatic compounds.
Metal Complex Formation: 5-Bromopicolinic acid can act as a ligand to form metal complexes. It can coordinate with metal ions through the lone pair of electrons on the nitrogen atom in the pyridine ring.
Oxidation/Reduction: Depending on the reaction conditions, 5-bromopicolinic acid can undergo oxidation or reduction reactions. For example, it can be oxidized to the corresponding carboxylic acid or reduced to the corresponding alcohol.
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5-Bromo-4-methylpyridine-2-carboxylic acid
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5-Bromo-3-(trifluoromethyl)-2-pyridinecarboxylic acid
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3-Amino-5-bromopyridine-2-carboxylic Acid
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