Chemistry Heterocyclic building blocks Piperidines Piperidin-2-ylmethanol

Piperidin-2-ylmethanol

These compounds have the same murcko framework: piperidin-2-ylmethanol

Oxidation: The hydroxymethyl group can be oxidized to form an aldehyde or carboxylic acid, depending on the conditions and reagents used.
Nucleophilic substitution: The hydroxymethyl group can undergo substitution reactions with suitable nucleophiles to form new compounds.
Acetylation: The hydroxyl group can be acetylated using acetic anhydrides or acetyl chloride to form the corresponding acetate ester.
Reduction: The carbonyl group of the piperidine ring can be reduced to form a secondary amine.
Ether formation: The hydroxyl group can undergo ether formation reactions with alkyl halides or alkyltosylates to form ethers.
Amination: The alcohol functionality can be converted into an amine through various methods, such as reductive amination or substitution.
Ring-opening reactions: The piperidine ring can undergo ring-opening reactions under specific conditions, yielding various products depending on the reagents and reaction conditions.

Further Reading:

Framework+−

(9h-fluoren-9-yl)methyl piperidine-1-carboxylate (e)-n-(3-oxo-1-phenyl-3-(piperidin-1-yl)prop-1-en-2-yl)benzamide (r)-2-phenylpiperidine (r)-3-aminopiperidin-2-one (r)-n-(piperidin-3-yl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine (s)-2-phenylpiperidine (s)-n-phenylpiperidine-2-carboxamide 1,3-dihydrospiro[indene-2,4'-piperidine] 1,4'-bipiperidine 1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid 1-((benzyloxy)carbonyl)piperidine-3-carboxylic acid 1-(methylsulfonyl)piperidine 1-(phenylsulfonyl)piperidine 1-(piperidin-1-yl)ethan-1-one 1-(piperidin-4-yl)piperazine 1-benzyl 3-methyl piperidine-1,3-dicarboxylate 1-benzyl-n-methylpiperidin-3-amine 1-benzylpiperidin-3-one 1-benzylpiperidin-4-amine 1-benzylpiperidin-4-one 1-isopropylpiperidine 1-methyl-4-phenylpiperidine 1-methylpiperidin-2-one 1-oxa-8-azaspiro[4.5]decane 1-phenylpiperidin-2-one 2,2-dimethylpiperidin-4-one 2,2-dimethylpiperidine 2,7-diazaspiro[3.5]nonane 2,8-diazaspiro[4.5]decan-3-one 2,8-diazaspiro[4.5]decane 2-(piperidin-1-yl)ethan-1-amine 2-(piperidin-1-yl)ethan-1-ol 2-(piperidin-1-yl)pyridine 2-(piperidin-1-yl)pyrimidine 2-(piperidin-2-yl)ethan-1-ol 2-(piperidin-4-yl)ethan-1-ol 2-(piperidin-4-yl)pyridine 2-methylpiperidin-4-one 2-methylpiperidine 2-phenylpiperidine 3,3-difluoropiperidin-4-one 3,3-difluoropiperidine 3,3-dimethylpiperidin-4-one 3,3-dimethylpiperidine 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione 3-(piperidin-1-yl)pyridine 3-(piperidin-4-yl)-1h-indazole 3-(piperidin-4-yl)-1h-indole 3-(piperidin-4-yl)pyridine 3-fluoropiperidin-4-one 3-fluoropiperidine 3-methoxypiperidine 3-methylpiperidin-4-one 3-methylpiperidine 3-phenylpiperidine 4,4-difluoropiperidine 4-(1h-pyrazol-1-yl)piperidine 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine 4-(azetidin-1-yl)piperidine 4-(benzyloxy)piperidine 4-(piperidin-1-yl)pyrimidine 4-(pyrrolidin-1-yl)piperidine 4-benzylpiperidine 4-hydrazineylpiperidine 4-hydroxypiperidin-2-one 4-methyl-1-phenylpiperidine 4-methylenepiperidine 4-oxopiperidine-2-carboxylic acid 4-phenylpiperidin-4-ol 5-hydroxypiperidin-2-one 6-azaspiro[2.5]octane 6-oxopiperidine-2-carboxylic acid 7-azaspiro[3.5]nonane Azepane Benzyl (r)-3-aminopiperidine-1-carboxylate Benzyl 3-hydroxypiperidine-1-carboxylate Benzyl 4-oxopiperidine-1-carboxylate Benzyl piperidin-4-ylcarbamate Benzyl piperidine-1-carboxylate Benzyl-3-aminopiperidine-1-carboxylate Ethyl piperidine-1-carboxylate Ethyl piperidine-2-carboxylate Ethyl piperidine-3-carboxylate Ethyl piperidine-4-carboxylate Methyl 4-oxopiperidine-2-carboxylate Methyl piperidine-2-carboxylate Methyl piperidine-3-carboxylate N-benzylpiperidin-4-amine N-methylpiperidin-3-amine N-phenylpiperidin-4-amine N-phenylpiperidine-2-carboxamide Phenyl(piperidin-1-yl)methanone Phenyl(piperidin-4-yl)methanone Piperidin-2-ylmethanamine Piperidin-2-ylmethanol Piperidin-3-amine Piperidin-3-ol Piperidin-3-one Piperidin-3-ylmethanamine Piperidin-3-ylmethanol Piperidin-4-amine Piperidin-4-ol Piperidin-4-ylmethanamine Piperidin-4-ylmethanol Piperidine-2,4-dione Piperidine-2,6-dione Piperidine-2-carboxylic acid Piperidine-3-carboxamide Piperidine-3-carboxylic acid Piperidine-4-carboxylic acid Quinuclidine Spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1h)-one Spiro[chromane-2,4'-piperidin]-4-one Spiro[indene-2,4'-piperidin]-1(3h)-one Spiro[indoline-3,4'-piperidin]-2-one Spiro[indoline-3,4'-piperidine] Tert-butyl (2-oxopiperidin-3-yl)carbamate Tert-butyl (6-oxopiperidin-3-yl)carbamate Tert-butyl (piperidin-3-ylmethyl)carbamate Tert-butyl 2-oxopiperidine-1-carboxylate Tert-butyl 3-bromopiperidine-1-carboxylate Tert-butyl 4-oxopiperidine-1-carboxylate Tert-butyl 4-phenoxypiperidine-1-carboxylate Tert-butyl 4-phenylpiperidine-1-carboxylate Tert-butyl piperidin-3-ylcarbamate

By Key Group+−

Acetylpiperidine Aminopiperidine Benzoylpiperidine Benzylpiperidine Bipiperidine Boc-piperidine Boronate-piperidine-carboxylate Bromopiperidine Carbamoylpiperidine Chloropiperidine Cyanopiperidine Cyclopropylpiperidin Difluoromethyl-piperidine Difluoropiperidine Dimethylpiperidine Dioxaborolane-piperidine Dioxopiperidine Ethylpiperidine Ethynylpiperidine Fluoropiperidine Formylpiperidine Hydroxyethyl-piperidine-carboxylate Hydroxymethyl-piperidine-carboxylate Hydroxypiperidine Indazole-piperidine-carboxylate Indoline-piperidine Isopropylpiperidine Methoxypiperidine Methylenepiperidine Methylpiperidine Oxoethyl-piperidine-carboxylate Oxopiperidine Pentamethylpiperidin Phenoxypiperidine Phenyl-sulfonyl-piperidine Phenylpiperidine Piperidin-amine Piperidin-imidazolyl Piperidine-benzimidazole Piperidine-benzofuran Piperidine-carboxylate Piperidine-carboxylate-hydrochloride Piperidine-carboxylic acid Piperidine-ethanol Piperidine-hydrochloride Piperidine-indole Piperidine-methanamine Piperidine-methanone Piperidine-nitrile Piperidine-piperidine Piperidine-propanol Piperidine-pyrimidine Piperidine-triazole Piperidineacetic Piperidinecarboxylate Piperidinecarboxylic Piperidinemethanol Piperidinone Piperidinyl-phenyl-boronic acid Piperidinyl-phenyl-boronic acid/ester Piperidinyl-phenyl-boronic-acid Propylpiperidine Pyrazole-piperidine Pyridin-piperidine Spiro-benzofuran-piperidine Tetrahydropyrazolopyridine Tetramethylpiperidine Trifluoromethyl-phenyl-piperidine Trifluoromethyl-piperidine

By Parent Nucleus+−

aliphatic heterocycles aromatic heterocycles azetidines benzimidazoles benzisoxazoles benzofurans benzoxazoles dioxolanes epoxides furans guanidines imidazoles imidazolidines imidazolines indazoles indoles indolines isoxazoles morpholines other aliphatic heterocycles other aromatic heterocycles oxadiazoles oxazines oxazolidines oxazolines oxetanes piperazines pyrazines pyrazoles pyridazines Pyridines Pyrimidines pyrrolidines quinazolines spiroes tetrahydrofurans tetrahydroisoquinolines tetrahydropyrans thiophenes triazoles

By Functional Group+−

acyl chlorides alcohols aldehydes aliphatic chain hydrocarbons aliphatic cyclic hydrocarbons alkenyls alkyls alkynyls amides amines aryls azoes benzyl chlorides bromides carboxylic acids Chiral building blocks chlorides difluoromethyls esters ethers fluorinated building blocks hydrazides hydrazines hydroxylamines iodides ketones nitriles nitroes oximes phenols phosphoruses sulfamides sulfonates sulfones sulfonic acids sulfonyl chlorides thioureas trifluoromethyls ureas

Heterocyclic related+−

Metal catalysts piperidines

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    By Configuration+−

    Typically In Stock
    Purity
    • Please Select
    • 99+%
    • 99%
    • 98+%
    • 98%
    • 97+%
    • 97%
    • 96+%
    • 96%
    • 95+%
    • 95%
    • 93%
    • 90+%
    • 90%
    Size
    • Please Select
    • 1mg
    • 2mg
    • 5mg
    • 10mg
    • 25mg
    • 50mg
    • 100mg
    • 250mg
    • 1g
    • 5g
    • 10g
    • 25g
    • 100g
    • 500g
    • 1000g
    • 1kg
    Clear Filters
    2-(Hydroxymethyl)piperidine

    click to sign in and save

    A1795803433-37-298%

    2-(Hydroxymethyl)piperidine

    $12.00/5g

    Detail
    (S)-1-Boc-2-(Hydroxymethyl)piperidine

    click to sign in and save

    A108056134441-93-397%

    (S)-1-Boc-2-(Hydroxymethyl)piperidine

    $10.00/100mg

    Detail
    tert-Butyl 2-(hydroxymethyl)piperidine-1-carboxylate

    click to sign in and save

    A533574157634-00-998%

    tert-Butyl 2-(hydroxymethyl)piperidine-1-carboxylate

    $10.00/1g

    Detail
    (R)-Piperidin-2-ylmethanol

    click to sign in and save

    A1505333197-44-297%

    (R)-Piperidin-2-ylmethanol

    $218.00/10g

    Detail
    (S)-Piperidin-2-ylmethanol

    click to sign in and save

    A22356841373-39-197%

    (S)-Piperidin-2-ylmethanol

    $115.00/10g

    Detail
    (2S,4S)-tert-Butyl 4-amino-2-(hydroxymethyl)piperidine-1-carboxylate

    click to sign in and save

    A2107642253105-54-197%

    (2S,4S)-tert-Butyl 4-amino-2-(hydroxymethyl)piperidine-1-carboxylate

    $132.00/250mg

    Detail
    (R)-(1-Methylpiperidin-2-yl)methanol

    click to sign in and save

    A37913268474-13-597%

    (R)-(1-Methylpiperidin-2-yl)methanol

    $44.00/1g

    Detail
    (S)-(1-Methylpiperidin-2-yl)methanol

    click to sign in and save

    A226507136030-04-195%

    (S)-(1-Methylpiperidin-2-yl)methanol

    $58.00/1g

    Detail
    1-Methyl-2-piperidinemethanol

    click to sign in and save

    A12885220845-34-598%

    1-Methyl-2-piperidinemethanol

    $293.00/500g

    Detail
    (R)-N-Boc-Piperidine-2-methanol

    click to sign in and save

    A136337134441-61-595%

    (R)-N-Boc-Piperidine-2-methanol

    $45.00/5g

    Detail
    1    page 1 of 1 Pages

    Inquiry