Chemistry Organometallic Reagents Organoborons 1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperazine

1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperazine

Suzuki Coupling: The boron atom in the dioxaborolane can be used for Suzuki coupling reactions with aryl or vinyl halides in the presence of a palladium catalyst to form new carbon-carbon bonds. This reaction is commonly used in organic synthesis to introduce aryl or vinyl groups into molecules. Amide Formation: The piperazine group can react with acyl chlorides or anhydrides to form amides. This reaction is known as acylation and is often used to modify organic compounds. Alkylation: The piperazine nitrogen atoms can undergo alkylation reactions with alkyl halides or sulfonates to introduce alkyl groups onto the piperazine ring. Deboronation: The boron atom in the dioxaborolane can be removed by treatment with acids or other reagents, resulting in the formation of a carbon-carbon bond at the boron-substituted position. Substitution Reactions: The benzyl group on the piperazine can undergo substitution reactions with various nucleophiles or electrophiles depending on the reaction conditions. Reductive Amination: The piperazine group can participate in reductive amination reactions, which involve the formation of secondary amines by reacting with carbonyl compounds in the presence of reducing agents. Hydrolysis: The compound can undergo hydrolysis reactions under acidic or basic conditions, leading to the cleavage of various bonds in the molecule.

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(1-(Tert-Butoxycarbonyl)-1H-Indol-2-Yl)Boronic Acid (1-Phenyl-1H-Pyrazol-4-Yl)Boronic Acid (1H-Indazol-4-Yl)Boronic Acid (1H-Indazol-6-Yl)Boronic Acid (1H-Indol-2-Yl)Boronic Acid (2,3-Dichlorophenyl)Boronic Acid (2,3-Difluorophenyl)Boronic Acid (2,6-Dichlorophenyl)Boronic Acid (2,6-Difluorophenyl)Boronic Acid (2-(Phenoxymethyl)Phenyl)Boronic Acid (2-(Trifluoromethoxy)Phenyl)Boronic Acid (2-(Trifluoromethyl)Phenyl)Boronic Acid (2-Bromophenyl)Boronic Acid (2-Chloro-3-Methoxyphenyl)Boronic Acid (2-Chloro-6-Fluorophenyl)Boronic Acid (2-Fluoro-3-(Trifluoromethyl)Phenyl)Boronic Acid (2-Fluorophenyl)Boronic Acid (2-Nitrophenyl)Boronic Acid (3,4-Dichlorophenyl)Boronic Acid (3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol (3-(Benzyloxy)Phenyl)Boronic Acid (3-(Phenoxymethyl)Phenyl)Boronic Acid (3-(Phenylcarbamoyl)Phenyl)Boronic Acid (3-(Trifluoromethoxy)Phenyl)Boronic Acid (3-(Trifluoromethyl)Phenyl)Boronic Acid (3-Bromo-2-Fluorophenyl)Boronic Acid (3-Bromo-2-Methoxyphenyl)Boronic Acid (3-Bromophenyl)Boronic Acid (3-Chloro-2-Methoxyphenyl)Boronic Acid (3-Chloro-4-Fluorophenyl)Boronic Acid (3-Chlorophenyl)Boronic Acid (3-Fluorophenyl)Boronic Acid (3-Iodophenyl)Boronic Acid (3-Nitrophenyl)Boronic Acid (4-(Benzyloxy)Phenyl)Boronic Acid (4-(Methylsulfonyl)Phenyl)Boronic Acid (4-(Phenoxymethyl)Phenyl)Boronic Acid (4-(Phenylcarbamoyl)Phenyl)Boronic Acid (4-(Trifluoromethyl)Phenyl)Boronic Acid (4-Cyclohexylphenyl)Boronic Acid (4-Fluorophenyl)Boronic Acid (5-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid (6-Phenoxypyridin-3-Yl)Boronic Acid (9H-Fluoren-2-Yl)Boronic Acid (E)-4,4,5,5-Tetramethyl-2-Styryl-1,3,2-Dioxaborolane 1,3,2-Dioxaborinane 1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperazine 1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Piperazine 1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperazine 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole 2,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-9H-Fluorene 2-(1,3,2-Dioxaborinan-2-Yl)Benzonitrile 2-(1,3,2-Dioxaborolan-2-Yl)-1-Methyl-1H-Indole 2-(2-(Bromomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(2-Bromophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(3-Chlorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(3-Cyclopropylphenyl)-1,3,2-Dioxaborolane 2-(3-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-(4-(Benzyloxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(4-Bromophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(4-Cyclopropylphenyl)-1,3,2-Dioxaborolane 2-(4-Fluorophenyl)-1,3,2-Dioxaborinane 2-([1,1'-Biphenyl]-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(Cyclohex-1-En-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(Furan-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-(M-Tolyl)-1,3,2-Dioxaborinane 2-Benzyl-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methoxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-(1,3,2-Dioxaborinan-2-Yl)Aniline 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 4,4,5,5-Tetramethyl-2-(2-(Trifluoromethyl)Phenyl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(2-Nitrophenyl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(3-(Trifluoromethoxy)Phenyl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Naphthalen-1-Yl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Naphthalen-2-Yl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Thiophen-2-Yl)-1,3,2-Dioxaborolane 4,4,5,5-Tetramethyl-2-(Thiophen-3-Yl)-1,3,2-Dioxaborolane 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2,3,6-Tetrahydropyridine 4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indoline 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nicotinonitrile 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidine 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole [1,1'-Biphenyl]-4-Ylboronic Acid Benzo[B]Thiophen-2-Ylboronic Acid Benzofuran-2-Ylboronic Acid Benzyl (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate Cyclohex-1-En-1-Ylboronic Acid Ethyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate Isoquinolin-4-Ylboronic Acid Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nicotinate N,N-Diphenyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline Naphthalen-1-Ylboronic Acid Naphthalen-2-Ylboronic Acid Phenylboronic Acid Pyridin-2-Ylboronic Acid Pyridin-3-Ylboronic Acid Pyridin-4-Ylboronic Acid Pyrimidin-5-Ylboronic Acid Tert-Butyl 2-(1,3,2-Dioxaborolan-2-Yl)-1H-Indole-1-Carboxylate Tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Carboxylate Tetraphenylborate Thiophen-2-Ylboronic Acid

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Alkenyl-Phenyl-Boronic-Acid Amino-Methyl-Phenyl-Borate Amino-Phenyl-Boronic-Acid Benzofuran-Boronic Acid Boronate-Piperidine-Carboxylate Bromophenyl-Boronate Bromopyridine-Boronate Butoxy-Phenyl-Boronic-Acid Carbazolyl-Phenyl-Boronic-Acid Carbonyl-Phenyl-Boronic-Acid Chloro-Phenyl-Boronic-Acid Chlorpyridine-Boronate Dimethyldioxaborane Dioxaborolan-Carbazole Dioxaborolan-Indazole Dioxaborolan-Indole Dioxaborolan-Methanol Dioxaborolan-Pyrazole Dioxaborolan-Pyrimidine Dioxaborolane Dioxaborolane-Benzene Dioxaborolane-Benzimidazole Dioxaborolane-Benzoxazole Dioxaborolane-Indene Dioxaborolane-Morpholine Dioxaborolane-Piperazine Dioxaborolane-Piperidine Dioxaborolane-Pyrrole Dioxaborolane-Pyrrolidine Dioxaborolane-Quinoline Dioxaborolane-Thiazole Fluorene-Boric Acid Fluorene-Boric-Acid Fluorene-Boronic Acid Fluorene-Dioxaborolane Fluorene-Phenyl-Boronic Acid Fluorene-Phenyl-Boronic Acid/Ester Fluorene-Phenyl-Boronic-Acid Fluoro-Phenyl-Boronic Acid Fluoro-Pyridine-Borate Fluorophenyl-Borate Formamidophenylboronic-Acid Hydroxymethyl-Phenyl-Boronic-Acid Hydroxyphenyl-Boronate Indazol-Boronic Acid Isopropoxyphenylboronic Isopropyl-Phenyl-Boronic-Acid Isoquinolin-Boronic-Acid Methoxy-Pyridine-Boronate Methoxyphenylboronic Acid Methoxyphenylboronic-Acid Methylthio-Phenyl-Boronic-Acid Naphthenic-Benzene-Boronic-Acid Phenyl-Boronate Phenyl-Boronic-Acid-Carboxylate Phenyl-Naphthalene-Boronic Acid Phenyl-Naphthalene-Boronic Acid/Ester Phenyl-Naphthalene-Boronic-Acid Phenylboronic Picoline-Boronate Piperidinyl-Phenyl-Boronic-Acid Potassium Methyltrifluoroborate Potassium Trifluoroborate Pyrazole-Phenyl-Boronic-Acid Pyridine-Boronate Pyridineamine-Borate Pyridineboronic Acid Pyridone Boronate Pyridyl-Benzene-Boronic-Acid Pyridyl-Phenyl-Borate Pyrrolidine-Benzene-Boronic-Acid Quinoline-Dioxaborolane Sulfonyl-Phenyl-Boronic Acid Thienyl-Benzene-Boronic-Acid Thiophene-Boronic Acid Trifluoromethyl-Phenyl-Borate Trifluoromethyl-Phenyl-Boronic Acid Trifluorotoluene-Dioxaborane

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    1-(4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazin-1-yl)ethanone

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    1-(4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazin-1-yl)ethanone

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    tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine-1-carboxylate

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    1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperazine

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    1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine dihydrochloride

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    1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine dihydrochloride

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    1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine hydrochloride

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    1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine hydrochloride

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