Home Chemistry Heterocyclic Building Blocks Pyridines (5-Bromopyridin-2-Yl)Methanol
Substitution Reactions: The bromine atom in the molecule can undergo substitution reactions with nucleophiles. For example, it can be replaced by other nucleophiles such as hydroxide ions, amines, or thiols, leading to the formation of different products.
Oxidation Reactions: The alcohol group (-OH) in the molecule can undergo oxidation reactions to form carbonyl compounds. For instance, it can be oxidized to an aldehyde or a carboxylic acid using oxidizing agents such as chromic acid, potassium permanganate, or Jones reagent.
Esterification: The alcohol group can undergo esterification reactions with carboxylic acids or acid chlorides in the presence of acid catalysts, forming esters.
Grignard Reaction: The compound can react with a Grignard reagent (an organomagnesium compound) to form a new carbon-carbon bond.
Reduction Reactions: The bromine atom can be reduced to form a bromide ion, while the alcohol group can be reduced to form an alkane or an aldehyde, depending on the reducing agent used.
Alkylation Reactions: The compound can undergo alkylation reactions where the alcohol group acts as a nucleophile attacking an alkyl halide, resulting in the formation of a new carbon-carbon bond.
Halogenation Reactions: The aromatic ring can undergo halogenation reactions with halogenating agents, leading to the introduction of halogen atoms onto the aromatic ring.
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(5-Bromo-3-(trifluoromethyl)pyridin-2-yl)methanol
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(5-Bromo-3-fluoropyridin-2-yl)methanol
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