Home Chemistry Organic Building Blocks Chlorides (3-Chloro-4-Fluorophenyl)Boronic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—F,—B(OH)2).
Reduction: Chlorobenzene can be reduced to form cyclohexane under certain conditions, often using strong reducing agents like sodium in the presence of 【alcohol|https://www.ambeed.com/alcohols.html】.
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Formation of 【esters|https://www.ambeed.com/esters.html】 and 【Amides|https://www.ambeed.com/amides.html】: Phenylboronic acid can react with 【alcohols|https://www.ambeed.com/alcohols.html】 or 【amines|https://www.ambeed.com/amines.html】 to form 【esters|https://www.ambeed.com/esters.html】 and 【amides|https://www.ambeed.com/amides.html】, respectively, under appropriate conditions.
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(3-Chloro-4-fluoro-5-isopropoxyphenyl)boronic acid
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(3-Chloro-4-fluoro-5-(methoxycarbonyl)phenyl)boronic acid
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(3-Chloro-5-ethoxy-4-fluorophenyl)boronic acid
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(5-Chloro-2,4-difluorophenyl)boronic acid
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(5-Chloro-4-fluoro-2-nitrophenyl)boronic acid
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(3-Chloro-2,4-difluorophenyl)boronic acid
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3,5-Dichloro-4-fluorophenylboronic acid
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