Home Chemistry Heterocyclic Building Blocks Pyrrolines 2,5-Dihydro-1H-Pyrrol-2-One
Acylation: You can acylate 2,5-dihydro-1H-pyrrol-2-one using acyl chlorides or anhydrides to form amides. This reaction can be catalyzed by a base or acid.
Alkylation: Alkyl halides or other alkylating agents can be used to alkylate the nitrogen atom in 2,5-dihydro-1H-pyrrol-2-one. This reaction can be base-catalyzed or occur under other conditions.
Ring Opening: Under certain conditions, 2,5-dihydro-1H-pyrrol-2-one can undergo ring-opening reactions to form linear amides or carboxylic acids.
Cyclization: Depending on the reaction conditions and reagents, 2,5-dihydro-1H-pyrrol-2-one can be involved in cyclization reactions to form various heterocyclic compounds.
Reduction: Reduction of the carbonyl group in 2,5-dihydro-1H-pyrrol-2-one can yield the corresponding alcohol.
Michael Addition: 2,5-dihydro-1H-pyrrol-2-one can participate in Michael addition reactions with various nucleophiles.
Condensation Reactions: It can be used in condensation reactions to form more complex compounds.
Substitution Reactions: The nitrogen atom can undergo substitution reactions with various electrophiles.
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(S)-3-Acetyl-4-hydroxy-5-methyl-1H-pyrrol-2(5H)-one
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tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate
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