Home Chemistry Heterocyclic Building Blocks Indoles 1H-Indol-3-Yl Acetate
Hydrolysis: The acetate group in 1H-indol-3-yl acetate can undergo hydrolysis under acidic or basic conditions, resulting in the formation of indole-3-carboxylic acid and acetic acid.
Nucleophilic Substitution: The indole nitrogen can act as a nucleophile and undergo substitution reactions. For example, it can react with alkyl halides or acyl halides to form substituted indole derivatives.
Esterification: The indole nitrogen can react with acyl chlorides or anhydridesto form amides.
Oxidation: The indole ring can undergo oxidation reactions under certain conditions. For instance, it may be oxidized to form indole-3-carboxylic acid.
Reduction: The indole ring can undergo reduction reactions to form dihydroindole derivatives. This may involve reducing agents like hydrogen gas or reducing agents such as sodium borohydride.
Grignard Reactions: The compound may participate in Grignard reactions where a Grignard reagent is added to the indole-3-yl acetate, leading to the formation of a new carbon-carbon bond.
Mannich Reaction: The indole nitrogen can participate in Mannich-type reactions where it reacts with formaldehyde and a secondary amine to form a β-amino carbonyl compound.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :