Home Chemistry Organic Building Blocks Bromides 1-Bromo-2-Chloro-4-Nitrobenzene
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—Cl,—NO2).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Nitration: Nitrobenzene can undergo nitration reactions, where a nitro group (-NO2) is introduced onto the benzene ring. This is typically achieved by treating nitrobenzene with a mixture of concentrated sulfuric acid and concentrated nitric acid.
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1-Bromo-2-chloro-5-fluoro-4-nitrobenzene
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1-(5-Bromo-4-chloro-2-nitrophenyl)ethanone
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