Home Chemistry Organic Building Blocks Iodides 1-Iodo-3-Methylbenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—CH3).
Metalation Reactions: Iodobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Alkylation: Similar to acylation, toluene can also undergo Friedel-Crafts alkylation reactions, where an alkyl group is introduced onto the benzene ring. Alkylation reactions also require a Lewis acid catalyst.
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4-Iodo-2-methyl-1-(trifluoromethyl)benzene
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