Home Chemistry Organic Building Blocks Chlorides 1-Chloro-2,3-Difluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—F).
Sandmeyer Reaction: Chlorobenzene can be converted to other aryl halides through the Sandmeyer reaction, involving replacement of the chlorine atom with other halogens.
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
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2-(2-Chloro-3,4-difluorophenyl)acetic acid
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1-(2-Chloro-3,4-difluorophenyl)ethan-1-one
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4-Chloro-2,3-difluorophenylboronic acid
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