Home Chemistry Organic Building Blocks Bromides 4-Bromo-3-Chloroaniline
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—Cl,—NH2).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Schiff Base Formation: Aniline can react with 【aldehydes|https://www.ambeed.com/aldehydes.html】 and 【ketones|https://www.ambeed.com/ketones.html】 to form Schiff bases, which are important intermediates in organic synthesis.
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4-Bromo-3-chloro-5-(trifluoromethyl)aniline
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Methyl 2-amino-5-bromo-4-chlorobenzoate
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