Home Chemistry Organic Building Blocks Chlorides 1-Chloro-3-(Trifluoromethoxy)Benzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—OCF3).
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Nucleophilic Aromatic Substitution (NAS): In some cases, under appropriate conditions, nucleophiles can attack the benzene ring, leading to nucleophilic aromatic substitution reactions. The trifluoromethoxy group can influence the reactivity of the ring.
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4-Chloro-2-(trifluoromethoxy)benzaldehyde
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1-Bromo-3-chloro-5-(trifluoromethoxy)benzene
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2-Chloro-1-iodo-4-(trifluoromethoxy)benzene
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1-Bromo-2-chloro-4-(trifluoromethoxy)benzene
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Methyl 2-amino-3-chloro-5-(trifluoromethoxy)benzoate
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3-Chloro-5-(trifluoromethoxy)benzaldehyde
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3'-Chloro-5'-(trifluoromethoxy)acetophenone
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4-Bromo-2-chloro-6-(trifluoromethoxy)aniline
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2-Chloro-1-nitro-4-(trifluoromethoxy)benzene
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2-Chloro-4-(trifluoromethoxy)benzaldehyde
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(2-Chloro-4-(trifluoromethoxy)phenyl)boronic acid
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