Home Chemistry Heterocyclic Building Blocks Pyridines 5-Bromo-2-Fluoropyridine
Nucleophilic substitution reactions: The bromine atom can be substituted by various nucleophiles such as amines, alkoxides, thiols, etc., to form corresponding substituted pyridines.
Cross-coupling reactions: 5-bromo-2-fluoropyridine can participate in Suzuki, Stille, Sonogashira, or Heck coupling reactions to form biaryl or heteroaryl compounds.
Metalation reactions: The bromine atom can be deprotonated using strong bases such as butyllithium or sodium amide to generate reactive intermediates that can undergo further transformations.
Electrophilic aromatic substitution reactions: The pyridine ring can undergo substitution reactions with electrophiles, leading to functionalization at the 2- or 5-position of the pyridine ring.
Redox reactions: 5-bromo-2-fluoropyridine can undergo oxidation or reduction reactions to form different functional groups or rearranged products.
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Potassium (5-bromo-2-fluoropyridin-3-yl)trifluoroborate
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1-(5-Bromo-2-fluoropyridin-3-yl)ethanone
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5-Bromo-3-(difluoromethyl)-2-fluoropyridine
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(5-Bromo-2-fluoropyridin-3-yl)methanamine hydrochloride
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