Home Chemistry Organic Building Blocks Iodides Methyl 4-Amino-3-Iodobenzoate
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —I,—NH2,—COOCH3).
Sandmeyer Reaction: Iodobenzene can undergo a Sandmeyer reaction, where it is treated with a copper(I) salt and a source of nitrogen. This leads to the replacement of the iodine atom with a new functional group, such as an 【amine|https://www.ambeed.com/amines.html】, 【azide|https://www.ambeed.com/azides.html】, or 【cyanide|https://www.ambeed.com/nitriles.html】.
Schiff Base Formation: Aniline can react with 【aldehydes|https://www.ambeed.com/aldehydes.html】 and 【ketones|https://www.ambeed.com/ketones.html】 to form Schiff bases, which are important intermediates in organic synthesis.
Fischer Esterification: Methyl benzoate can be synthesized through Fischer esterification, where benzoic acid reacts with methanol in the presence of an acid catalyst, typically sulfuric acid. This reaction forms the ester bond and releases water as a byproduct.
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