STK33 (Serine/Threonine Kinase 33) belongs to the serine/threonine kinase family, featuring a typical kinase activity domain. It is mainly located in the cytoplasm and is involved in signaling pathways that regulate cell growth and survival. The expression of STK33 is abnormally elevated in various types of cancer cells, suggesting its significant role in carcinogenesis. Mutations or changes in expression can affect cell cycle regulation and apoptosis, with further research needed to reveal its specific mechanisms in disease.