Home Chemistry Organic Building Blocks Bromides 2-Bromo-4-Methylbenzoic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—COOH,—CH3).
Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Decarboxylation: Under certain conditions, benzoic acid can undergo decarboxylation, where it loses a carbon dioxide molecule from its carboxylic acid group. This reaction usually requires high temperatures and is often observed in the presence of strong acids or bases.
Alkylation: Similar to acylation, toluene can also undergo Friedel-Crafts alkylation reactions, where an alkyl group is introduced onto the benzene ring. Alkylation reactions also require a Lewis acid catalyst.
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