Chemistry Heterocyclic Building Blocks Benzofurans

Benzofurans

Benzofuran, a colorless liquid present in coal tar, is a heterocyclic compound that comprises fused benzene and furan rings. It serves as the precursor of numerous related compounds with more intricate structures.

Benzofurans exhibit a low degree of aromaticity and are susceptible to cleavage under various oxidative and reductive conditions. Additionally, concentrated mineral acids and Lewis acids can induce their polymerization.

Benzofuran, a fused ring system of benzene and furan, is an important oxygen-containing heterocycle with potent biological properties. It is widely found in naturally occurring and synthetically derived compounds and exhibits antifungal, antibacterial, antiviral, and anti-inflammatory activities.

Benzofurans that have been substituted are utilized in a variety of fields including drug discovery, chemistry, agriculture, and as fluorescent sensors and oxidants.

Benzofuran derivatives, which are oxygen-containing heterocycles, hold significant importance. Compounds containing benzofuran skeletons, whether naturally occurring or artificially synthesized, have demonstrated exceptional activity as pharmaceuticals and agrochemicals.

More >>

Further Reading:
>>
More Skeleton screening
✕ ✕ ✕ ✕ ✕ ✕

Framework+−

1-(benzofuran-2-yl)ethan-1-one 2,2-dimethyl-2,3-dihydrobenzofuran 2,3-dihydrobenzofuran-3-amine 2,3-dihydrobenzofuran-5-amine 2,3-dihydrobenzofuran-7-amine 2-(benzofuran-3-yl)acetic acid 2-bromodibenzo[b,d]furan 2-ethylbenzofuran 2-methylbenzofuran 3-methylbenzofuran 4-bromobenzofuran 4-phenyldibenzo[b,d]furan 5,7,8-trimethylchromane 5-bromo-2,3-dihydrobenzofuran 5-chloro-2,3-dihydrobenzofuran 5-fluoro-2,3-dihydrobenzofuran 5-methoxyisobenzofuran-1(3H)-one 6-bromo-2,3-dihydrobenzofuran 6-fluoro-2,3-dihydrobenzofuran 6-methoxybenzofuran 7-bromo-2,3-dihydrobenzofuran 7-bromobenzofuran 7-fluoro-2,3-dihydrobenzofuran benzofuran-2(3H)-one benzofuran-2-carbaldehyde benzofuran-2-carboxylic acid benzofuran-2-ylboronic acid benzofuran-3(2H)-one benzofuran-3-carboxylic acid benzofuran-3-yl(phenyl)methanone methyl benzofuran-2-carboxylate

By Key Group+−

aminobenzofuran benzofuran-amine benzofuran-boronic acid benzofuran-carbonitrile benzofuran-carboxylate benzofuran-carboxylic acid benzofuran-carboxylic-acid benzofuran-dioxaborolane benzofuran-hydrochloride benzofuran-methanol benzofuran-one benzofuranocarbazole benzofuranopyrimidine bromobenzofuran bromoisobenzofuran chlorobenzofuran chloroisobenzofuran dihydrobenzofuran dihydroisobenzofuran dimethoxyisobenzofuran epoxyisobenzofuran ethylbenzofuran fluorobenzofuran fluoroisobenzofuran hexahydroisobenzofuran hydroxy-benzofuran hydroxybenzofuran hydroxyisobenzofuran iodo-benzofuran iodoisobenzofuran isobenzofuran methoxybenzofuran methoxyisobenzofuran methylbenzofuran methylbenzofuro methylisobenzofuran nitrobenzofuran nitroisobenzofuran other benzofuran phenyl-benzofuran piperidine-benzofuran spiro-benzofuran-piperidine tetrahydrobenzofuran

By Parent Nucleus+−

Aromatic Heterocycles Indoles Other Aromatic Heterocycles Piperazines Piperidines Spiroes

By Functional Group+−

Alcohols Aldehydes Alkenyls Amides Amines Anhydrides Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Iodides Ketones Nitriles Nitroes Phenols Sulfamides Sulfonyl Chlorides

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    6-Methoxy-3-phenyl-1-benzofuran-2-carboxylic acid

    click to sign in and save

    A111217058468-43-295%

    6-Methoxy-3-phenyl-1-benzofuran-2-carboxylic acid

    $354.00/5g

    Detail
    6-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid

    click to sign in and save

    A11127981208402-13-495%

    6-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid

    $83.00/250mg

    Detail
    Ethyl 6-methoxy-3-phenylbenzofuran-2-carboxylate

    click to sign in and save

    A144099858468-42-197%

    Ethyl 6-methoxy-3-phenylbenzofuran-2-carboxylate

    $25.00/100mg

    Detail
    2,4-Dichlorobenzofuro[3,2-d]pyrimidine

    click to sign in and save

    A844556160199-95-197%

    2,4-Dichlorobenzofuro[3,2-d]pyrimidine

    $245.00/5g

    Detail
    Dibenzo[b,d]furan-2-carbonitrile

    click to sign in and save

    A67596520927-96-295+%

    Dibenzo[b,d]furan-2-carbonitrile

    $115.00/1g

    Detail
    2-(10-(Naphthalen-2-yl)anthracen-9-yl)dibenzo[b,d]furan

    click to sign in and save

    A16970511226809-67-198%

    2-(10-(Naphthalen-2-yl)anthracen-9-yl)dibenzo[b,d]furan

    $55.00/1g

    Detail
    (S)-6-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride

    click to sign in and save

    A13731342489613-16-198%

    (S)-6-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride

    $102.00/250mg

    Detail
    5-Fluorobenzofuran-2-carboxylic acid

    click to sign in and save

    A50982689197-62-695%

    5-Fluorobenzofuran-2-carboxylic acid

    $58.00/1g

    Detail
    (R)-7-Bromo-2,3-dihydrobenzofuran-3-amine

    click to sign in and save

    A4843351213092-51-397%

    (R)-7-Bromo-2,3-dihydrobenzofuran-3-amine

    $517.00/250mg

    Detail
    3-Methoxyisobenzofuran-1(3H)-one

    click to sign in and save

    A6302214122-57-098%

    3-Methoxyisobenzofuran-1(3H)-one

    $15.00/250mg

    Detail
    Benzofuran-3-carbaldehyde

    click to sign in and save

    A1876464687-25-695%

    Benzofuran-3-carbaldehyde

    $26.00/1g

    Detail
    (S)-2-(Benzofuran-2-carboxamido)-2-phenylacetic acid

    click to sign in and save

    A10898411217756-92-795%

    (S)-2-(Benzofuran-2-carboxamido)-2-phenylacetic acid

    $43.00/100mg

    Detail
    2,3-Dihydrobenzofuran-6-carbaldehyde

    click to sign in and save

    A21190055745-96-598%

    2,3-Dihydrobenzofuran-6-carbaldehyde

    $227.00/250mg

    Detail
    7-Chlorobenzofuran

    click to sign in and save

    A37778524410-55-796%

    7-Chlorobenzofuran

    $22.00/250mg

    Detail
    2-Bromo-4-phenyldibenzo[b,d]furan

    click to sign in and save

    A14864062025367-17-198%

    2-Bromo-4-phenyldibenzo[b,d]furan

    $36.00/250mg

    Detail
    4-(4-Bromophenyl)dibenzo[b,d]furan

    click to sign in and save

    A267985955959-84-996%

    4-(4-Bromophenyl)dibenzo[b,d]furan

    $259.00/100g

    Detail
    6-Fluoro-4-nitroisobenzofuran-1(3H)-one

    click to sign in and save

    A1391651207453-90-495%

    6-Fluoro-4-nitroisobenzofuran-1(3H)-one

    $11.00/1g

    Detail
    5-Bromo-2,3-dihydrobenzofuran-3-amine hydrochloride

    click to sign in and save

    A5293261187927-75-896%

    5-Bromo-2,3-dihydrobenzofuran-3-amine hydrochloride

    $1309.00/5g

    Detail
    Benzofuran-5-ylboronic acid

    click to sign in and save

    A129428331834-13-097%

    Benzofuran-5-ylboronic acid

    $23.00/1g

    Detail
    2-Benzofuranyl methyl ketone

    click to sign in and save

    A8050591646-26-098%

    2-Benzofuranyl methyl ketone

    $18.00/5g

    Detail
    1 2 3 4 5 6 7 8 9 ...    page 1 of 186 Pages

    Inquiry