Chemistry Organic building blocks Iodides 4-bromo-2-chloro-1-iodobenzene

4-bromo-2-chloro-1-iodobenzene

These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —I,—Cl,—Br).

Sandmeyer Reaction: Iodobenzene can undergo a Sandmeyer reaction, where it is treated with a copper(I) salt and a source of nitrogen. This leads to the replacement of the iodine atom with a new functional group, such as an 【amine|https://www.ambeed.com/amines.html】, 【azide|https://www.ambeed.com/azides.html】, or 【cyanide|https://www.ambeed.com/nitriles.html】.
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.

Further Reading:

Framework+−

(2-iodophenyl)(phenyl)methanone (2-iodophenyl)methanol (3-iodophenyl)boronic acid (3-iodophenyl)methanol 1,2-benziodoxol-3-(1h)-one 1,2-difluoro-3-iodobenzene 1,2-diiodobenzene 1,3-dibromo-2-iodobenzene 1,3-dichloro-2-iodobenzene 1,3-difluoro-2-iodobenzene 1,3-diiodo-2-phenoxybenzene 1,3-diiodobenzene 1,4-dibromo-2-iodobenzene 1,4-difluoro-2-iodobenzene 1-(2-iodophenyl)ethan-1-one 1-(3-iodophenyl)ethan-1-one 1-(benzyloxy)-4-iodobenzene 1-(bromomethyl)-2-iodobenzene 1-benzyl-4-iodo-1h-pyrazole 1-bromo-2-iodobenzene 1-bromo-3-fluoro-2-iodobenzene 1-bromo-3-iodobenzene 1-bromo-4-iodobenzene 1-chloro-2-fluoro-3-iodobenzene 1-chloro-2-iodobenzene 1-chloro-3-iodo-2-methylbenzene 1-chloro-3-iodobenzene 1-chloro-4-iodobenzene 1-ethyl-2-iodobenzene 1-fluoro-2-iodo-4-methylbenzene 1-fluoro-2-iodobenzene 1-fluoro-3-iodo-2-methylbenzene 1-fluoro-3-iodobenzene 1-fluoro-4-iodobenzene 1-iodo-2,3-dimethylbenzene 1-iodo-2,4-dimethylbenzene 1-iodo-2-(trifluoromethoxy)benzene 1-iodo-2-(trifluoromethyl)benzene 1-iodo-2-isopropylbenzene 1-iodo-2-methoxybenzene 1-iodo-2-methylbenzene 1-iodo-2-nitrobenzene 1-iodo-3-(trifluoromethoxy)benzene 1-iodo-3-(trifluoromethyl)benzene 1-iodo-3-methoxybenzene 1-iodo-3-methylbenzene 1-iodo-3-nitrobenzene 1-iodo-4-methoxybenzene 1-iodo-4-phenoxybenzene 2,4-difluoro-1-iodobenzene 2,6-dichloro-4-iodopyridine 2,6-diiodoaniline 2,6-diiodophenol 2-bromo-3-iodopyridine 2-bromo-4-chloro-1-iodobenzene 2-bromo-6-iodoaniline 2-bromo-6-iodopyridine 2-chloro-3-iodopyridin-4-amine 2-chloro-3-iodopyridine 2-chloro-4-iodopyridine 2-chloro-5-iodopyridine 2-chloro-6-iodophenol 2-chloro-6-iodopyridine 2-fluoro-1-iodo-4-methylbenzene 2-fluoro-3-iodopyridine 2-fluoro-6-iodoaniline 2-hydroxy-3-iodobenzaldehyde 2-iodo-1,3-dimethylbenzene 2-iodo-1,4-dimethylbenzene 2-iodo-1-methyl-4-nitrobenzene 2-iodo-4-methylaniline 2-iodo-6-methylpyridine 2-iodo-6-nitroaniline 2-iodo-9h-fluorene 2-iodo-n,n-dimethylaniline 2-iodoaniline 2-iodobenzaldehyde 2-iodobenzamide 2-iodobenzene-1,3-diol 2-iodobenzoic acid 2-iodobenzonitrile 2-iodonaphthalene 2-iodophenol 2-iodopyrazine 2-iodopyridine 2-iodopyrimidine 2-iodothiophene 3-chloro-2-iodoaniline 3-chloro-4-iodoaniline 3-fluoro-2-iodoaniline 3-iodo-1-methyl-1h-pyrazole 3-iodo-1h-pyrrolo[2,3-b]pyridine 3-iodo-1h-pyrrolo[3,2-b]pyridine 3-iodo-2-methylaniline 3-iodoaniline 3-iodobenzaldehyde 3-iodobenzoic acid 3-iodobenzonitrile 3-iodoimidazo[1,2-a]pyridine 3-iodophenol 3-iodopyridazine 3-iodopyridin-2-amine 3-iodopyridin-2-ol 3-iodopyridin-4-amine 3-iodopyridin-4-ol 3-iodopyridine 3-iodotetrahydrofuran 4-bromo-2-chloro-1-iodobenzene 4-bromo-2-fluoro-1-iodobenzene 4-bromo-2-iodoaniline 4-chloro-2-iodoaniline 4-chloro-3-iodoaniline 4-chloro-5-iodopyrimidine 4-fluoro-2-iodoaniline 4-fluoro-3-iodobenzoic acid 4-iodo-1,1'-biphenyl 4-iodo-1h-pyrazole 4-iodo-n,n-diphenylaniline 4-iodopyridine 4-iodopyrimidine 5-bromo-2-iodopyridine 5-iodo-1h-imidazole 5-iodo-1h-pyrazole 5-iodo-7h-pyrrolo[2,3-d]pyrimidine 5-iodopyridin-2-amine 5-iodopyridin-2-ol 5-iodopyrimidine 6-chloro-5-iodopyridin-2-amine Ethyl 2-iodobenzoate Ethyl 3-iodobenzoate Methyl 2-iodobenzoate Methyl 3-iodo-4-methylbenzoate Methyl 3-iodobenzoate Methyl 4-amino-3-iodobenzoate N-(2-iodophenyl)acetamide Phenyl(o-tolyl)iodonium Tert-butyl 3-iodo-1h-indole-1-carboxylate

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3-iodopropyl Diiodo Diiodobenzoate Fluoro-iodo-nitro-benzene Fluoroiodobenzene Iodo-benzofuran Iodo-fluorene Iodo-indazol-amine Iodo-indazole Iodo-indazole-carboxylate Iodo-indole Iodo-isoquinoline Iodo-methyl-pyrazole Iodo-pyrazole-carboxylate Iodo-pyrazolopyridine Iodo-pyrrolopyridine Iodo-pyrrolopyridine-carboxylate Iodo-pyrrolopyrimidine Iodo-trifluoromethyl-pyridine Iodoacetate Iodoaniline Iodoanisole Iodobenzaldehyde Iodobenzamide Iodobenzene Iodobenzoate Iodobenzotrifluoride Iodobutane Iodobutane Iodoethane Iodoethane Iodoethoxy Iodoethoxy Iodoethyl Iodoethyl Iodohexane Iodohexane Iodoimidazo Iodomethyl Iodomethyl Iodomethyl-imidazole Iodomethyl-indazole Iodonicotinaldehyde Iodonicotinate Iodonicotinic Iodonicotinic Iodonitrobenzene Iodopropane Iodopropane Iodopropyl Iodopropyl Iodopyrazolo Iodopyrimidine Iodotoluene

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