Chemistry Heterocyclic Building Blocks Pyridines Nicotinonitrile

Nicotinonitrile

These compounds have the same murcko framework: nicotinonitrile

Nucleophilic Substitution: Nicotinonitrile can undergo nucleophilic substitution reactions at the carbon atom adjacent to the nitrogen atom. This can result in the replacement of the nitrile group with other nucleophiles, such as hydroxide ions (OH⁻), amines, or thiolates.
Hydrolysis: Nicotinonitrile can undergo hydrolysis under acidic or basic conditions, leading to the cleavage of the carbon-nitrogen triple bond and the formation of carboxylic acids or amides, depending on the reaction conditions.
Reduction: Nicotinonitrile can be reduced to form various derivatives, such as pyridine or piperidine, by using reducing agents like hydrogen gas (H2) in the presence of a catalyst (e.g., Raney nickel) or metal hydrides (e.g., lithium aluminum hydride, LAH).
Addition Reactions: Nicotinonitrile can undergo addition reactions with electrophiles, such as acids or alkylating agents, at the nitrogen or carbon atoms, resulting in the formation of substituted derivatives.
Ring-Forming Reactions: Nicotinonitrile can participate in ring-forming reactions, such as cyclization or condensation reactions, leading to the formation of heterocyclic compounds containing nitrogen atoms in the ring structure.
Oxidation: Nicotinonitrile can undergo oxidation reactions to form various oxidation products, such as nicotinic acid or its derivatives.

Further Reading:

Framework+−

(2-Chloropyridin-4-Yl)Boronic Acid (3-Bromopyridin-2-Yl)Methanol (3-Chloropyridin-2-Yl)Methanamine (3-Fluoropyridin-2-Yl)Methanamine (3-Methylpyridin-2-Yl)Methanamine (3-Methylpyridin-2-Yl)Methanol (3Ar,8As)-2-(Pyridin-2-Yl)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole (3As,8Ar)-2-(Pyridin-2-Yl)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole (4R,5S)-4,5-Diphenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (5-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid (5-Bromopyridin-2-Yl)Methanamine (5-Bromopyridin-2-Yl)Methanol (5-Chloropyridin-2-Yl)Methanamine (6-Methylpyridin-2-Yl)Methanamine (6-Methylpyridin-2-Yl)Methanol (6-Phenoxypyridin-3-Yl)Boronic Acid (R)-3-(Pyrrolidin-2-Yl)Pyridine (R)-4-Benzyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (R)-4-Phenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-(Tert-Butyl)-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-Benzyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-Isopropyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole (S)-4-Phenyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole 1,1'-Diphenyl-[4,4'-Bipyridine]-1,1'-Diium 1,10-Phenanthrolin-4-Ol 1,2,3,4-Tetrahydropyrido[2,3-B]Pyrazine 1,2,3,6-Tetrahydropyridine 1,3-Dihydro-2H-Pyrrolo[2,3-B]Pyridin-2-One 1,3-Dihydro-2H-Pyrrolo[2,3-C]Pyridin-2-One 1,3-Dihydro-2H-Pyrrolo[3,2-B]Pyridin-2-One 1,4-Di(Pyridin-4-Yl)Benzene 1-(5-Bromopyridin-2-Yl)Piperazine 1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine 1-(Pyridin-2-Yl)Ethan-1-Amine 1-(Pyridin-2-Yl)Ethan-1-One 1-(Pyridin-2-Yl-L2-Azaneyl)Ethan-1-One 1-(Pyridin-3-Yl)Ethan-1-Amine 1-(Pyridin-3-Yl)Ethan-1-One 1-(Pyridin-3-Yl)Piperazine 1-(Pyridin-3-Ylmethyl)Piperazine 1-(Pyridin-4-Yl)Ethan-1-Amine 1-(Pyridin-4-Yl)Ethan-1-One 1-Benzyl-1,2,3,6-Tetrahydropyridine 1-Benzyl-1H-Pyrazolo[3,4-B]Pyridine 1-Methyl-4-(Pyridin-2-Yl)Piperazine 1-Methylpyridin-1-Ium Iodide 1-Phenyl-3-(4-(Pyridin-4-Yloxy)Phenyl)Urea 1H-Imidazo[4,5-B]Pyridine 1H-Imidazo[4,5-C]Pyridine 1H-Pyrazolo[3,4-B]Pyridin-5-Amine 1H-Pyrrolo[2,3-C]Pyridin-7-Ol 1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid 1H-Pyrrolo[3,2-B]Pyridine-3-Carboxylic Acid 2,2':6',2''-Terpyridine 2,2-Dimethyl-1-(Pyridin-2-Yl-L2-Azaneyl)Propan-1-One 2,3'-Bipyridine 2,3,4,5-Tetrahydro-1H-Pyrido[4,3-B]Indole 2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole 2,3,5-Trichloropyridine 2,3,6-Trichloropyridine 2,3-Dibromopyridine 2,3-Dichloropyridine 2,3-Difluoropyridine 2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine 2,3-Dihydro-1H-Pyrrolo[2,3-C]Pyridine 2,3-Dihydro-1H-Pyrrolo[3,2-C]Pyridine 2,3-Dihydro-1H-Pyrrolo[3,4-C]Pyridine 2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine 2,3-Dihydropyridin-2-One 2,3-Dimethoxypyridine 2,3-Dimethylpyridine 2,4,6-Trichloropyridine 2,4,6-Triphenylpyridine 2,4-Dibromopyridine 2,4-Dichloro-6-Methylpyridine 2,4-Dichloropyridine 2,4-Dimethylpyridine 2,5-Dibromopyridine 2,5-Dichloropyridine 2,5-Difluoropyridine 2,6-Bis(4,5-Dihydrooxazol-2-Yl)Pyridine 2,6-Di(1H-Pyrazol-1-Yl)Pyridine 2,6-Dibromo-3-Fluoropyridine 2,6-Dibromopyridin-4-Amine 2,6-Dibromopyridine 2,6-Dichloro-3-Fluoropyridine 2,6-Dichloro-3-Methylpyridine 2,6-Dichloro-3-Nitropyridine 2,6-Dichloro-4-Iodopyridine 2,6-Dichloro-4-Methylpyridine 2,6-Dichloronicotinonitrile 2,6-Dichloropyridin-3-Amine 2,6-Dichloropyridine 2,6-Difluoropyridine 2,6-Dimethoxypyridine 2,6-Dimethylpyridin-4-Ol 2,6-Dimethylpyridine 2-(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-3-Yl)Pyridine 2-(2,2,2-Trifluoroethoxy)Pyridine 2-(2-Chlorophenyl)Pyridine 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-(4-Fluorophenyl)Pyridine 2-(6-Benzhydrylpyridin-2-Yl)-4,5-Dihydrooxazole 2-(6-Cyclopropylpyridin-2-Yl)-4,5-Dihydrooxazole 2-(Benzyloxy)Pyridine 2-(Bromomethyl)Pyridine 2-(Chloromethyl)-3-Methylpyridine 2-(Chloromethyl)Pyridine 2-(Chloromethyl)Pyridine 1-Oxide 2-(Difluoromethyl)Pyridine 2-(Methylsulfonyl)Pyridine 2-(Methylthio)Pyridine 2-(P-Tolyl)Pyridine 2-(Phenoxymethyl)Pyridine 2-(Piperidin-1-Yl)Pyridine 2-(Piperidin-4-Yl)Pyridine 2-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole 2-(Pyridin-2-Yl)Acetonitrile 2-(Pyridin-2-Yl)Pyrimidine 2-(Pyridin-2-Ylmethyl)-4,5-Dihydrooxazole 2-(Pyridin-3-Yl)Acetic Acid 2-(Pyridin-3-Yl)Acetonitrile 2-(Pyrrolidin-2-Yl)Pyridine 2-(Thiophen-2-Yl)Pyridine 2-(Tributylstannyl)Pyridine 2-(Trifluoromethoxy)Pyridine 2-(Trifluoromethyl)Pyridine 2-Aminonicotinonitrile 2-Benzylpyridine 2-Bromo-3-(Trifluoromethyl)Pyridine 2-Bromo-3-Chloropyridine 2-Bromo-3-Fluoropyridine 2-Bromo-3-Iodopyridine 2-Bromo-3-Methoxypyridine 2-Bromo-3-Methylpyridine 2-Bromo-3-Nitropyridine 2-Bromo-4-Chloropyridine 2-Bromo-4-Methylpyridine 2-Bromo-5-(Trifluoromethyl)Pyridine 2-Bromo-5-Chloropyridine 2-Bromo-5-Fluoropyridine 2-Bromo-5-Methoxypyridine 2-Bromo-5-Methylpyridine 2-Bromo-5-Nitropyridine 2-Bromo-6-(Trifluoromethyl)Pyridine 2-Bromo-6-Chloropyridine 2-Bromo-6-Fluoropyridine 2-Bromo-6-Iodopyridine 2-Bromo-6-Methoxypyridine 2-Bromo-6-Methylpyridine 2-Bromo-6-Phenylpyridine 2-Bromonicotinic Acid 2-Bromopyridin-3-Amine 2-Bromopyridin-3-Ol 2-Bromopyridine 2-Bromopyridine 1-Oxide 2-Chloro-3,6-Dimethylpyridine 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Chloro-3-(Trifluoromethyl)Pyridine 2-Chloro-3-Fluoropyridin-4-Amine 2-Chloro-3-Fluoropyridine 2-Chloro-3-Iodopyridin-4-Amine 2-Chloro-3-Iodopyridine 2-Chloro-3-Methoxypyridine 2-Chloro-3-Methylpyridine 2-Chloro-3-Nitropyridine 2-Chloro-4,6-Dimethylpyridine 2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Chloro-4-(Trifluoromethyl)Pyridine 2-Chloro-4-Ethoxypyridine 2-Chloro-4-Fluoropyridine 2-Chloro-4-Iodopyridine 2-Chloro-4-Methoxypyridine 2-Chloro-4-Methylpyridine 2-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Chloro-5-(Trifluoromethyl)Pyridine 2-Chloro-5-Fluoropyridin-4-Amine 2-Chloro-5-Fluoropyridine 2-Chloro-5-Iodopyridine 2-Chloro-5-Methylpyridine 2-Chloro-5-Nitropyridine 2-Chloro-6-(Trifluoromethyl)Pyridine 2-Chloro-6-Fluoropyridine 2-Chloro-6-Iodopyridine 2-Chloro-6-Methoxypyridine 2-Chloro-6-Methyl-3-Nitropyridine 2-Chloro-6-Methylnicotinonitrile 2-Chloro-6-Methylpyridine 2-Chloroisonicotinaldehyde 2-Chloroisonicotinic Acid 2-Chloroisonicotinonitrile 2-Chloronicotinic Acid 2-Chloronicotinonitrile 2-Chloropyridin-3-Amine 2-Chloropyridin-3-Ol 2-Chloropyridin-4-Amine 2-Chloropyridine 1-Oxide 2-Cyclopropyl-4-Phenylquinoline 2-Cyclopropylpyridine 2-Ethoxypyridine 2-Ethylpyridine 2-Ethynylpyridine 2-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Fluoro-3-Iodopyridine 2-Fluoro-3-Methylpyridine 2-Fluoro-4-Methylpyridine 2-Fluoro-5-Methoxypyridine 2-Fluoro-5-Methylpyridine 2-Fluoro-6-Methoxypyridine 2-Fluoro-6-Methylpyridine 2-Fluoropyridine 2-Hydrazineylpyridine 2-Iodo-6-Methylpyridine 2-Iodopyridine 2-Isopropoxypyridine 2-Isopropylpyridine 2-Methoxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methoxy-3-(Trifluoromethyl)Pyridine 2-Methoxy-4-Methylpyridine 2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methoxy-5-(Trifluoromethyl)Pyridine 2-Methoxy-5-Methylpyridine 2-Methoxy-5-Nitropyridine 2-Methoxy-6-Methylpyridine 2-Methoxyisonicotinic Acid 2-Methoxypyridin-3-Amine 2-Methoxypyridine 2-Methyl-1,10-Phenanthroline 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methyl-3-Nitropyridine 2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 2-Methylimidazo[1,2-A]Pyridine 2-Methylpyridin-3-Ol 2-Methylpyridin-4-Amine 2-Methylpyridine 1-Oxide 2-Nitropyridine 2-Phenoxy-5-(Trifluoromethyl)Pyridine 2-Phenylimidazo[1,2-A]Pyridine 2-Propoxypyridine 2H-Pyrido[3,2-B][1,4]Oxazin-3(4H)-One 3,3'-Bipyridine 3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine 3,5-Dibromopyridine 3,5-Dichloropyridine 3,5-Difluoropyridine 3,5-Dimethoxypyridine 3,5-Dimethylpyridine 3,5-Diphenylpyridine 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-5-(Trifluoromethyl)Pyridine 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-(Benzyloxy)Pyridine 3-(Bromomethyl)Pyridine 3-(Chloromethyl)Pyridine 3-(Cyclopropylmethyl)Pyridine 3-(Difluoromethyl)Pyridine 3-(Methylsulfonyl)Pyridine 3-(Piperidin-1-Yl)Pyridine 3-(Piperidin-4-Yl)Pyridine 3-(Pyrrolidin-2-Yl)Pyridine 3-(Tert-Butyl)Pyridine 3-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine 3-(Trifluoromethyl)Pyridin-2-Ol 3-(Trifluoromethyl)Pyridine 3-Bromo-1H-Pyrrolo[3,2-B]Pyridine 3-Bromo-2-Chloropyridin-4-Amine 3-Bromo-2-Chloropyridine 3-Bromo-2-Fluoropyridine 3-Bromo-2-Methoxypyridine 3-Bromo-2-Methylpyridine 3-Bromo-4-Methylpyridine 3-Bromo-5-Chloropyridine 3-Bromo-5-Fluoropyridine 3-Bromo-5-Methylpyridine 3-Bromo-5-Nitropyridine 3-Bromopicolinic Acid 3-Bromopicolinonitrile 3-Bromopyrazolo[1,5-A]Pyridine 3-Bromopyridin-2-Amine 3-Bromopyridin-2-Ol 3-Bromopyridine 1-Oxide 3-Chloro-2-Fluoropyridine 3-Chloro-2-Methoxypyridine 3-Chloro-2-Methylpyridine 3-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-Chloro-5-Fluoropyridine 3-Chloro-5-Methylpyridine 3-Chloro-5-Nitropyridine 3-Chloroimidazo[1,2-A]Pyridine 3-Chloropicolinic Acid 3-Chloropicolinonitrile 3-Chloropyridin-2-Amine 3-Chloropyridin-2-Ol 3-Cyclopropylpyridine 3-Ethoxypyridine 3-Ethylpyridine 3-Ethynylpyridine 3-Fluoro-2-Methoxypyridine 3-Fluoro-2-Methylpyridine 3-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-Fluoropicolinic Acid 3-Fluoropicolinonitrile 3-Fluoropyridin-2-Amine 3-Fluoropyridin-4-Amine 3-Hydrazineylpyridine 3-Iodo-1H-Pyrazolo[3,4-B]Pyridine 3-Iodo-1H-Pyrrolo[3,2-B]Pyridine 3-Iodo-1H-Pyrrolo[3,2-C]Pyridine 3-Iodopyridin-2-Amine 3-Iodopyridin-2-Ol 3-Iodopyridin-4-Amine 3-Iodopyridin-4-Ol 3-Iodopyridine 3-Methoxypyridin-2-Amine 3-Methoxypyridine 3-Methyl-1H-Pyrrolo[2,3-B]Pyridine 3-Methyl-2-Phenylpyridine 3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 3-Methyl-5-Nitropyridine 3-Methylimidazo[1,2-A]Pyridine 3-Methylpicolinic Acid 3-Methylpyridin-2-Amine 3-Methylpyridine 3-Methylpyridine 1-Oxide 3-Nitropyridin-2-Ol 3-Nitropyridin-4-Amine 3-Nitropyridine 3-Phenoxypyridine 4'-Phenyl-2,2':6',2''-Terpyridine 4,4'-Bipyridine 4,5,6,7-Tetrahydro-1H-Pyrazolo[3,4-C]Pyridine 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine 4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine 4,5,6,7-Tetrahydrothiazolo[5,4-C]Pyridine 4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine 4,5,6,7-Tetrahydrothieno[3,2-C]Pyridine 4,6-Dichloropyridin-2-Amine 4,6-Dichloropyridin-3-Amine 4,7-Diphenyl-1,10-Phenanthroline 4-(2,4-Diphenyl-1H-Imidazol-5-Yl)Pyridine 4-(Benzyloxy)Pyridine 4-(Bromomethyl)Pyridine 4-(Pyridin-2-Yl)Morpholine 4-(Pyridin-3-Yl)Pyrimidine 4-(Pyridin-4-Yl)Morpholine 4-(Tert-Butyl)-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole 4-(Tert-Butyl)Pyridine 4-(Trifluoromethyl)Nicotinic Acid 4-(Trifluoromethyl)Pyridine 4-Bromo-2-Chloropyridine 4-Bromo-2-Fluoropyridine 4-Bromo-2-Methoxypyridine 4-Bromo-3-Methylpyridine 4-Bromopyrazolo[1,5-A]Pyridine 4-Bromopyridine 4-Chloro-1H-Pyrazolo[4,3-C]Pyridine 4-Chloro-1H-Pyrrolo[2,3-B]Pyridine 4-Chloro-1H-Pyrrolo[3,2-C]Pyridine 4-Chloro-2,6-Dimethylpyridine 4-Chloro-2-Methoxypyridine 4-Chloro-3-Methylpyridine 4-Chloronicotinic Acid 4-Chloropyridin-2-Amine 4-Chloropyridine 4-Cyclopropylpyridine 4-Ethoxypyridine 4-Ethynylpyridine 4-Iodopyridine 4-Isopropyl-2-(Pyridin-2-Yl)-4,5-Dihydrooxazole 4-Methoxypyridine 4-Methyl-2,2'-Bipyridine 4-Methyl-2-Phenylpyridine 4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine 4-Methyl-3-Nitropyridine 4-Methylnicotinic Acid 4-Methylpyridine 4-Nitropyridine 4-Phenoxypyridine 4-Phenyl-1,2,3,6-Tetrahydropyridine 4-Phenyl-1,4-Dihydropyridine 5,6,7,8-Tetrahydroimidazo[1,2-A]Pyridine 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine 5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine 5,6-Dichloropyridin-2-Amine 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nicotinonitrile 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine 5-(Trifluoromethyl)Pyridin-2-Amine 5-(Trifluoromethyl)Pyridin-2-Ol 5-Benzyl-4,5,6,7-Tetrahydrothieno[3,2-C]Pyridine 5-Bromo-2-Chloro-4-Methylpyridine 5-Bromo-2-Chloropyridine 5-Bromo-2-Fluoropyridine 5-Bromo-2-Iodopyridine 5-Bromo-2-Methoxypyridine 5-Bromo-2-Methylpyridine 5-Bromo-2-Phenylpyridine 5-Bromo-4-Methylpyridin-2-Amine 5-Bromo-6-Chloropyridin-2-Amine 5-Bromonicotinaldehyde 5-Bromonicotinic Acid 5-Bromonicotinonitrile 5-Bromopicolinic Acid 5-Bromopicolinonitrile 5-Bromopyridin-2-Amine 5-Bromopyridin-2-Ol 5-Bromopyridin-3-Amine 5-Bromopyridin-3-Ol 5-Chloro-1H-Pyrazolo[3,4-B]Pyridine 5-Chloro-1H-Pyrazolo[4,3-B]Pyridine 5-Chloro-1H-Pyrrolo[2,3-C]Pyridine 5-Chloro-1H-Pyrrolo[3,2-B]Pyridine 5-Chloro-2-Fluoropyridine 5-Chloro-2-Methoxypyridine 5-Chloro-2-Methylpyridine 5-Chloroimidazo[1,2-A]Pyridine 5-Chloropicolinic Acid 5-Chloropicolinonitrile 5-Chloropyridin-2-Amine 5-Chloropyridin-2-Ol 5-Chloropyridin-3-Amine 5-Fluoro-2-Methoxypyridine 5-Fluoro-2-Methylpyridine 5-Fluoropicolinonitrile 5-Fluoropyridin-2-Amine 5-Iodopyridin-2-Amine 5-Iodopyridin-2-Ol 5-Methoxy-1H-Pyrrolo[2,3-C]Pyridine 5-Methoxypyridin-3-Amine 5-Methylimidazo[1,2-A]Pyridine 5-Methylpyridin-2-Amine 5-Methylpyridin-3-Amine 5-Nitronicotinic Acid 5-Nitropyridin-2-Amine 5-Phenylpicolinic Acid 6,7-Dihydro-5H-Cyclopenta[B]Pyridine 6,7-Dihydro-5H-Cyclopenta[C]Pyridine 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridine 6-(Trifluoromethyl)Pyridin-2-Amine 6-(Trifluoromethyl)Pyridin-3-Amine 6-Bromo-1H-Pyrazolo[4,3-B]Pyridine 6-Bromo-1H-Pyrrolo[3,2-B]Pyridine 6-Bromo-1H-Pyrrolo[3,2-C]Pyridine 6-Bromoimidazo[1,2-A]Pyridine 6-Bromonicotinaldehyde 6-Bromonicotinic Acid 6-Bromonicotinonitrile 6-Bromopicolinic Acid 6-Bromopyrazolo[1,5-A]Pyridine 6-Bromopyridin-2-Amine 6-Bromopyridin-3-Amine 6-Bromopyridin-3-Ol 6-Chloro-1H-Pyrazolo[4,3-C]Pyridine 6-Chloro-1H-Pyrrolo[3,2-C]Pyridine 6-Chloro-3-Nitropyridin-2-Amine 6-Chloro-5-(Trifluoromethyl)Pyridin-2-Amine 6-Chloro-5-Iodopyridin-2-Amine 6-Chloroimidazo[1,2-A]Pyridine 6-Chloronicotinaldehyde 6-Chloronicotinic Acid 6-Chloropicolinic Acid 6-Chloropicolinonitrile 6-Chloropyridin-2-Amine 6-Chloropyridin-2-Ol 6-Chloropyridin-3-Amine 6-Chloropyridine-3-Sulfonyl Chloride 6-Fluoro-1H-Pyrrolo[2,3-B]Pyridine 6-Fluoropyridin-2-Amine 6-Fluoropyridin-3-Amine 6-Methoxy-1H-Pyrrolo[2,3-B]Pyridine 6-Methoxynicotinaldehyde 6-Methoxypicolinic Acid 6-Methoxypyridin-2-Amine 6-Methoxypyridin-3-Amine 6-Methylnicotinic Acid 6-Methylnicotinonitrile 6-Methylpicolinic Acid 6-Methylpicolinonitrile 6-Methylpyridin-2-Amine 6-Methylpyridin-2-Ol 6-Methylpyridin-3-Amine 6-Methylpyridin-3-Ol 6-Phenoxypyridin-3-Amine 6-Phenylnicotinic Acid 6-Phenylpicolinic Acid 7-Bromo-1H-Pyrrolo[2,3-C]Pyridine 7-Chloro-1H-Pyrrolo[2,3-C]Pyridine 7-Methoxy-1H-Pyrrolo[2,3-C]Pyridine 7-Methylimidazo[1,2-A]Pyridine 9H-Pyrido[3,4-B]Indole Bis(Pyridin-2-Ylmethyl)Amine Dimethyl Pyridine-2,6-Dicarboxylate Dimethyl(Pyridin-2-Yl)Phosphine Oxide Dimethyl(Pyridin-3-Yl)Phosphine Oxide Ethyl 2-(Pyridin-2-Yl)Acetate Ethyl 2-Methylnicotinate Ethyl 4,6-Dichloronicotinate Ethyl 6-Chloropicolinate Ethyl Isonicotinate Ethyl Nicotinate Ethyl Picolinate Ethyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Furo[3,2-B]Pyridine Furo[3,2-C]Pyridine Imidazo[1,2-A]Pyridin-2-Ylmethanol Imidazo[1,2-A]Pyridine-5-Carboxylic Acid Imidazo[1,2-A]Pyridine-6-Carbonitrile Isonicotinaldehyde Isonicotinamide Isonicotinic Acid Isonicotinohydrazide Isonicotinonitrile Methyl 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate Methyl 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylate Methyl 2-(Pyridin-2-Yl)Acetate Methyl 2-Chloroisonicotinate Methyl 2-Chloronicotinate Methyl 3-Bromopicolinate Methyl 3-Chloropicolinate Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Nicotinate Methyl 5-Hydroxypicolinate Methyl 6-Bromonicotinate Methyl 6-Chloropicolinate Methyl 6-Fluoronicotinate Methyl 6-Methoxynicotinate Methyl Isonicotinate Methyl Nicotinate Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate N,N-Dimethylpyridin-2-Amine N,N-Dimethylpyridin-4-Amine N-(Pyridin-2-Yl)Benzamide N-Benzylpyridin-2-Amine N-Methylpicolinamide N-Methylpyridin-2-Amine N-Methylpyridin-3-Amine N-Phenyl-4-(Pyridin-3-Yl)Pyrimidin-2-Amine N-Phenylpicolinamide N-Phenylpyridin-2-Amine Nicotinaldehyde Nicotinamide Nicotinic Acid Nicotinonitrile Oxazolo[4,5-B]Pyridine Oxazolo[5,4-B]Pyridine Phenyl(Pyridin-2-Yl)Methanone Phenyl(Pyridin-3-Yl)Methanone Picolinaldehyde Picolinamide Picolinic Acid Picolinimidamide Picolinohydrazide Pyrazolo[1,5-A]Pyridine-2-Carboxylic Acid Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid Pyridin-2-Amine Pyridin-2-Ol Pyridin-2-Ylboronic Acid Pyridin-2-Ylmethanamine Pyridin-2-Ylmethanol Pyridin-3-Amine Pyridin-3-Ol Pyridin-3-Ylboronic Acid Pyridin-3-Ylmethanamine Pyridin-3-Ylmethanol Pyridin-4-Amine Pyridin-4-Ol Pyridin-4-Ylboronic Acid Pyridin-4-Ylmethanamine Pyridin-4-Ylmethanol Pyridine 1-Oxide Pyridine-2,3-Diamine Pyridine-2,6-Diamine Pyridine-2,6-Dicarboxylic Acid Pyridine-2,6-Diol Pyridine-2-Sulfonamide Pyridine-2-Sulfonyl Chloride Pyridine-2-Thiol Pyridine-3-Sulfonic Acid Pyridine-3-Sulfonyl Chloride Pyrido[2,3-B]Pyrazine Pyrido[2,3-D]Pyrimidine Pyrido[3,2-D]Pyrimidine Pyrido[3,4-B]Pyrazine Pyrido[3,4-D]Pyrimidine Tert-Butyl (2-Chloropyridin-4-Yl)Carbamate Tert-Butyl 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate Tert-Butyl 4-(Pyridin-2-Yl)Piperazine-1-Carboxylate Tert-Butyl Pyridin-2-Ylcarbamate Tert-Butyl Pyridin-3-Ylcarbamate Tert-Butyl Pyridin-4-Ylcarbamate Thiazolo[4,5-B]Pyridine Thiazolo[5,4-B]Pyridine Thiazolo[5,4-C]Pyridine Thieno[2,3-B]Pyridine Thieno[2,3-C]Pyridine Thieno[3,2-B]Pyridine Thieno[3,2-C]Pyridine

By Key Group+−

2-Pyridone Derivatives Acetylpyridin Aminopicolinate Aminopicolinic Aminopyridine Benzyloxypyridine Bipyridine Bromo-Picolin-Amide Bromopicolinaldehyde Bromopicolinate Bromopicolinic Bromopicolinic Acid Bromopicolinonitrile Bromopyridine Bromopyrido Bromotriazolopyridine Butylpyridine Carbazo-Pyridine Chloro-Pyrrolopyridine-Carboxylate Chloro-Triazolopyridine Chloroisonicotinic Chloroisonicotinic Acid Chloronicotinaldehyde Chloronicotinamide Chloronicotinate Chloronicotinic Chloropyridine Chlorpyridine-Boronate Cyanopicolinate Cyanopicolinic Cyanopyridine Cyclopropoxypyridine Cyclopropylpyridine Dibromopicolinate Dibromopicolinic Dibromopicolinic Acid Dibromopyridine Dichloropicolinate Dichloropicolinic Dichloropicolinonitrile Dichloropyridine Difluoromethyl-Pyridine Difluoronicotinic Difluoropicolinic Difluoropicolinic Acid Difluoropyridine Dihydropyridine Dihydropyrido Dihydroxy-Pyridine Dihydroxypyridine Diiodopyridine Dimethoxypicolinic Dimethoxypicolinic Acid Dimethoxypyridine Dimethylpyridine Diphenylpyridine Dipicolinamide Dipyridine Ethoxypicolinic Ethoxypicolinic Acid Ethoxypyridine Ethylpyridine Ethynylpicolinate Ethynylpyridine Fluoro-Pyridine--Boronate Fluoro-Pyridine-Borate Fluoro-Pyridine-Borolane Fluoro-Triazolopyridine Fluoro-Trifluoromethyl-Pyridine Fluoropicolinaldehyde Fluoropicolinamide Fluoropicolinate Fluoropyridine Fluoropyrido Formylpicolinate Formylpyridine Furopyridine Hexahydropyrido Hydrazinylpyridine Hydroxymethylpyridine Hydroxypicolinate Hydroxypicolinic Hydroxypicolinonitrile Hydroxypyridine Imidazol-Pyridine Imidazopyridin-Amine Imidazopyridine Iodo-Pyrazolopyridine Iodopicolinate Iodopicolinic Iodopicolinic Acid Iodopyridine Isonicotinic Isopropoxypyridine Isopropylpyridine Methoxy-Pyridine-Boronate Methoxy-Pyrrolopyridine Methoxy-Trifluoromethyl-Pyridine Methoxyisonicotinaldehyde Methoxynicotinaldehyde Methoxypicolinaldehyde Methoxypicolinamide Methoxypicolinate Methoxypicolinic Methoxypicolinic Acid Methoxypicolinimidamide Methoxypicolinonitrile Methoxypyridine Methyl-Imidazopyridine Methyl-Pyrazolopyridine Methyl-Pyrrolopyridine Methyl-Triazolopyridine Methylisonicotinamide Methylisonicotinate Methylnicotinaldehyde Methylnicotinamide Methylpicolinaldehyde Methylpicolinamide Methylpicolinate Methylpicolinic Methylpicolinonitrile Methylpyridine Methylpyrido Nitropyridine Oxadiazo-Pyridine Oxazolopyridine Oxopyridin Phenoxypyridin Phenylpicolinate Phenylpyridine Picolinate Picoline-Boronate Picolinic Piperazine-Pyridine Pyranopyridine Pyrazol-Pyridine Pyrazolopyridin-Ol Pyrazolopyridine Pyridin-Benzene Pyridin-Benzoimidazole Pyridin-Ethanamine Pyridin-Methanamine Pyridin-Piperidine Pyridin-Pyrimidin Pyridin-Quinoline Pyridinamine Pyridine-Boronate Pyridine-Hydrochloride Pyridine-Propylamine Pyridine-Pyrazole Pyridine-Pyrrole Pyridine-Pyrrolidine Pyridine-Thiazol-Amide Pyridine-Thiazole Pyridineboronic Acid Pyridinecarbonitrile Pyridinecarboxylate Pyridinecarboxylic Pyridinemethanol Pyridinoindole Pyridinone Pyridonaphthyridine Pyridone Boronate Pyridooxazin-One Pyridopyrazine Pyridopyrimidin Pyridoxazine Pyridyl-Benzene-Boronic Acid Pyridyl-Benzene-Boronic Acid/Ester Pyridyl-Benzene-Boronic-Acid Pyridyl-Ethanol Pyridyl-Morpholine Pyridyl-Phenyl-Borate Pyridyl-Phenyl-Boronate Pyridyl-Triazine Pyridylmethyl Pyrrolidin-Pyridine Pyrrolopyridine Pyrrolopyridine-Carboxylate Pyrrolopyrimidin-Amine Terpyridine Tetrachloropyridine Tetrafluoropyridine Tetrahydropyrazolopyridine Tetrahydropyridine Tetrahydropyrido Thiazolopyridine Thienopyridine Triazol-Pyridine Triazolopyridin-Amine Triazolopyridine Triazolopyridine-Carboxylate Triazolopyridine-Carboxylic Tribromopyridine Trichloropyridine Trichloropyrido Trifluoromethyl-Pyridin-Amine Trifluoromethyl-Pyridine-Ethylamine Trifluoromethyl-Pyridyl-Methanamine Trifluoromethylpyridine Trifluoropyridine Trimethylpyridine

By Parent Nucleus+−

Aliphatic Heterocycles Aromatic Heterocycles Azetidines Benzimidazoles Dioxolanes Guanidines Imidazoles Indazoles Indoles Indolines Morpholines Other Aliphatic Heterocycles Other Aromatic Heterocycles Oxazolines Oxetanes Piperazines Piperidines Purines Pyrazoles Pyrimidines Pyrroles Pyrrolidines Quinolines Spiroes Tetrahydropyrans Tetrahydroquinolines Thiadiazoles Thiazoles Thiazolidines Thiophenes Thiophenols Triazines Triazoles

By Functional Group+−

Acyl Chlorides Alcohols Aldehydes Aliphatic Chain Hydrocarbons Aliphatic Cyclic Hydrocarbons Alkenyls Alkyls Alkynyls Amides Amidines Amines Aryls Benzyl Bromides Benzyl Chlorides Bromides Carboxylic Acid Salts Carboxylic Acids Chiral Building Blocks Chlorides Difluoromethyls Esters Ethers Fluorinated Building Blocks Hydrazides Hydrazines Hydrazones Hydroxylamines Iodides Ketones Nitriles Nitroes Oximes Phenols Phosphoruses Sulfamides Sulfides Sulfonates Sulfones Sulfonic Acids Sulfonyl Chlorides Sulfoxides Thioesters Thioureas Trifluoromethyls Ureas

Heterocyclic related+−

Py

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    Typically In Stock
    Purity
    • Please Select
    • 99+%
    • 99%
    • 98+%
    • 98%
    • 97+%
    • 97%
    • 96+%
    • 96%
    • 95+%
    • 95%
    • 93%
    • 90+%
    • 90%
    Size
    • Please Select
    • 1mg
    • 2mg
    • 5mg
    • 10mg
    • 25mg
    • 50mg
    • 100mg
    • 250mg
    • 1g
    • 5g
    • 10g
    • 25g
    • 100g
    • 500g
    • 1000g
    • 1kg
    Clear Filters
    6-Amino-4-chloro-3-pyridinecarbonitrile

    click to sign in and save

    A991524670253-38-098%

    6-Amino-4-chloro-3-pyridinecarbonitrile

    $236.00/1g

    Detail
    4-Chloro-2-methylnicotinonitrile

    click to sign in and save

    A5126191261487-92-695%

    4-Chloro-2-methylnicotinonitrile

    $822.00/1g

    Detail
    4-Chloronicotinonitrile

    click to sign in and save

    A14956689284-61-795%

    4-Chloronicotinonitrile

    $285.00/10g

    Detail
    4-Bromo-3-cyanopyridine

    click to sign in and save

    A600712154237-70-495%

    4-Bromo-3-cyanopyridine

    $176.00/5g

    Detail
    6-Amino-4-methylnicotinonitrile

    click to sign in and save

    A441321179555-10-397%

    6-Amino-4-methylnicotinonitrile

    $115.00/5g

    Detail
    4-Aminonicotinonitrile

    click to sign in and save

    A82542615827-84-696%

    4-Aminonicotinonitrile

    $18.00/100mg

    Detail
    4-Formylnicotinonitrile

    click to sign in and save

    A1998371060802-57-497%

    4-Formylnicotinonitrile

    $164.00/100mg

    Detail
    4-Methoxynicotinonitrile

    click to sign in and save

    A27187174133-20-397%

    4-Methoxynicotinonitrile

    $15.00/250mg

    Detail
    Pyridine-3,4-dicarbonitrile

    click to sign in and save

    A1460041633-44-995%

    Pyridine-3,4-dicarbonitrile

    $79.00/100mg

    Detail
    3-Cyanoisonicotinic acid

    click to sign in and save

    A7526401060802-59-695%

    3-Cyanoisonicotinic acid

    $48.00/100mg

    Detail
    Methyl 3-cyanoisonicotinate

    click to sign in and save

    A42481036106-47-595%

    Methyl 3-cyanoisonicotinate

    $465.00/5g

    Detail
    Methyl 2-(3-cyanopyridin-4-yl)acetate

    click to sign in and save

    A571150124870-33-397%

    Methyl 2-(3-cyanopyridin-4-yl)acetate

    $170.00/1g

    Detail
    2-Amino-3-methyl-5-cyanopyridine

    click to sign in and save

    A163368183428-91-398%

    2-Amino-3-methyl-5-cyanopyridine

    $50.00/1g

    Detail
    5-Methylpyridine-3-carbonitrile

    click to sign in and save

    A83604542885-14-397%

    5-Methylpyridine-3-carbonitrile

    $11.00/250mg

    Detail
    5-Aminonicotinonitrile

    click to sign in and save

    A23187813600-47-097%

    5-Aminonicotinonitrile

    $12.00/100mg

    Detail
    5-(Aminomethyl)nicotinonitrile hydrochloride

    click to sign in and save

    A8389532198774-67-195%

    5-(Aminomethyl)nicotinonitrile hydrochloride

    $186.00/100mg

    Detail
    Pyridine-3,5-dicarbonitrile

    click to sign in and save

    A1053581195-58-095%

    Pyridine-3,5-dicarbonitrile

    $42.00/100mg

    Detail
    2-Amino-5-cyanopyridine

    click to sign in and save

    A4536124214-73-798%

    2-Amino-5-cyanopyridine

    $1070.00/500g

    Detail
    6-(Cyanomethyl)nicotinonitrile

    click to sign in and save

    A1217841000516-33-597%

    6-(Cyanomethyl)nicotinonitrile

    $43.00/100mg

    Detail
    6-(tert-Butyl)nicotinonitrile

    click to sign in and save

    A60922456029-45-995+%

    6-(tert-Butyl)nicotinonitrile

    $50.00/1g

    Detail
    1 2 3 4 5    page 1 of 5 Pages

    Inquiry