Home Chemistry Heterocyclic Building Blocks Pyridines 2-Methoxy-4-Methylpyridine
Substitution Reactions: The methoxy and methyl groups can be substituted with other functional groups under appropriate conditions. For instance, halogenation reactions can replace these groups with halogens like chlorine or bromine.
Acylation: The nitrogen atom in the pyridine ring can undergo acylation reactions with acyl chlorides or acid anhydrides to form amides.
Oxidation Reactions: The methyl group can be oxidized to a carboxylic acid group under certain conditions, such as using strong oxidizing agents like potassium permanganate or chromic acid.
Reduction Reactions: The pyridine ring can be reduced to piperidine, especially under catalytic hydrogenation conditions.
Alkylation: The nitrogen atom in the pyridine ring can be alkylated with alkyl halides or alkyl sulfonates, leading to N-alkylated derivatives.
Condensation Reactions: It can undergo condensation reactions with carbonyl compounds to form β-alkoxy ketones or β-alkoxy aldehydes.
Nucleophilic Aromatic Substitution (S[sub]N[/sub]Ar): The methoxy group can act as a nucleophile in S[sub]N[/sub]Ar reactions, substituting other groups attached to the pyridine ring.
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6-Methoxy-4-methylpyridin-3-ylboronic acid
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