Home Chemistry Heterocyclic Building Blocks Thiazolidines 1,2,3-Oxathiazolidine 2,2-Dioxide
Hydrolysis: 1,2,3-Oxathiazolidine 2,2-dioxide can undergo hydrolysis in the presence of water to yield the corresponding carboxylic acid.
Oxidation: Depending on the reaction conditions, 1,2,3-oxathiazolidine 2,2-dioxide can be oxidized to produce various products. Oxidizing agents like hydrogen peroxide, bromine, or permanganate can be used for this purpose.
Ring-Opening Reactions: The thiazolidine ring can be opened under certain conditions, producing compounds with open-chain structures. This can be achieved by using appropriate nucleophiles or reagents that cleave the ring.
Substitution Reactions: The sulfur and oxygen atoms in the thiazolidine 2,2-dioxide ring can undergo substitution reactions with suitable reagents to introduce various functional groups.
Reduction: 1,2,3-Oxathiazolidine 2,2-dioxide can be reduced to form the corresponding thiol or other reduced products using reducing agents like sodium borohydride or lithium aluminum hydride.
Acylation: The compound can be acylated to introduce acyl groups into the molecule, often in the presence of acylating agents such as acyl chlorides or anhydrides.
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(S)-tert-Butyl 4-(tert-butyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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(R)-tert-Butyl 4-(tert-butyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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tert-Butyl 1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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(R)-3-Boc-4-methyl-1,2,3-oxathiazolidine 2,2-Dioxide
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(S)-tert-Butyl 4-ethyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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(S)-tert-Butyl 4-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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3-Boc-5,5-dimethyl-1,2,3-oxathiazolidine 2,2-Dioxide
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(R)-tert-Butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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(S)-tert-Butyl 4-isobutyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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(R)-tert-Butyl 4-isobutyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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(S)-tert-Butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide
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