Home Chemistry Organic Building Blocks Iodides 1-Iodo-2,3-Dimethylbenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—CH3).
Sandmeyer Reaction: Iodobenzene can undergo a Sandmeyer reaction, where it is treated with a copper(I) salt and a source of nitrogen. This leads to the replacement of the iodine atom with a new functional group, such as an 【amine|https://www.ambeed.com/amines.html】, 【azide|https://www.ambeed.com/azides.html】, or 【cyanide|https://www.ambeed.com/nitriles.html】.
Nitration: Toluene can undergo nitration, where a nitro group (-NO2) is introduced onto the benzene ring. This reaction usually requires the presence of concentrated nitric acid and sulfuric acid as a catalyst.
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