Home Chemistry Heterocyclic Building Blocks Quinolines N-Phenylquinolin-4-Amine
Acylation: N-Phenylquinolin-4-amine can be acylated with acylating agents like acyl chlorides or anhydrides to introduce acyl groups onto the amino group. For example, reacting it with acetyl chloride would yield N-phenylquinolin-4-amine acetate.
Amination: You can perform reductive amination to introduce different amino groups onto the compound. This involves reacting the amine with an appropriate aldehyde or ketone in the presence of a reducing agent.
Oxidation: N-Phenylquinolin-4-amine can be oxidized using strong oxidizing agents, such as potassium permanganate or chromic acid, to convert the amine group to a nitro group or other oxidation products.
Alkylation: The compound can be alkylated using alkyl halides or alkyl sulfonates to introduce alkyl groups onto the amino group or the aromatic ring.
Mannich Reaction: N-Phenylquinolin-4-amine can undergo the Mannich reaction with formaldehyde and a secondary amine to form aminomethylated derivatives.
Reduction: The nitro group, if present, can be reduced to an amino group using reducing agents like hydrogen and a metal catalyst.
Substitution Reactions: N-Phenylquinolin-4-amine can undergo electrophilic aromatic substitution reactions, such as Friedel-Crafts acylation or Friedel-Crafts alkylation, on the aromatic ring under appropriate conditions.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
click to sign in and save
4-((7-Fluoroquinolin-4-yl)amino)benzoic acid
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :