Home Chemistry Heterocyclic Building Blocks Pyridines 3-Bromo-2-Methoxypyridine
Substitution Reactions: The bromine atom can undergo substitution reactions, such as nucleophilic substitution or metal-halogen exchange reactions.
Nucleophilic Aromatic Substitution (SNAr): The electron-deficient pyridine ring can undergo nucleophilic aromatic substitution reactions, where a nucleophile substitutes for the bromine atom.
Cross-Coupling Reactions: The bromine atom can undergo pyridine-catalyzed cross-coupling reactions, such as Suzuki, Heck, or Stille couplings, to form new carbon-carbon bonds.
Metalation Reactions: The pyridine ring can be metalated at the 3-position using strong bases, leading to further functionalization or coupling reactions.
Reductive Reactions: The bromine atom can be replaced with a hydrogen atom via reductive reactions using metal catalysts or reducing agents.
Oxidation Reactions: The methyl group or the methoxy group can undergo oxidation reactions to introduce functional groups like aldehydes, ketones, or carboxylic acids.
Amination Reactions: The bromine atom can undergo amination reactions to introduce amino groups into the molecule.
Halogenation Reactions: The pyridine ring can undergo halogenation reactions under appropriate conditions.
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