Home Chemistry Organic Building Blocks Sulfides Benzyl(Phenyl)Sulfane
Oxidation: Benzyl(phenyl)sulfane can be oxidized to form benzyl(phenyl)sulfoxide (C6H5CH2S(=O)Ph) and further to benzyl(phenyl)sulfone (C6H5CH2SO2Ph) using various oxidizing agents like hydrogen peroxide (H2O2) or m-chloroperoxybenzoic acid (m-CPBA).
Reduction: The compound can be reduced to the corresponding sulfide using reducing agents such as sodium borohydride (NaBH4).
Substitution reactions: The benzyl group and phenyl group can be subject to substitution reactions. For example, the benzyl group can be converted to the benzyl chloride (C6H5CH2Cl) or benzyl bromide (C6H5CH2Br) by reacting with hydrogen chloride (HCl) or hydrogen bromide (HBr), respectively. Similarly, the phenyl group can undergo substitution reactions.
Nucleophilic reactions: The sulfur atom can be subject to nucleophilic attack by strong nucleophiles. For example, thiols or alkoxides can displace the benzyl group in SN2 reactions.
Cross-coupling reactions: The benzyl(phenyl)sulfane can participate in various cross-coupling reactions, such as Suzuki-Miyaura or Heck reactions, to form carbon-carbon or carbon-heteroatom bonds.
Hydrolysis: Benzyl(phenyl)sulfane can be hydrolyzed under acidic or basic conditions to yield the corresponding benzoic acid and phenylsulfonic acid.
Grignard reactions: Benzyl(phenyl)sulfane can react with Grignard reagents to form a new carbon-carbon bond.
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(E)-Ethyl 3-(2-amino-5-(benzylthio)phenyl)acrylate
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3,4-Difluoro-2-((phenylthio)methyl)benzoic acid
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