Home Chemistry Heterocyclic Building Blocks Piperidines Piperidine-2,6-Dione
Reduction: Piperidine-2,6-dione can be reduced to piperidine-2,6-diol using reducing agents like sodium borohydride (NaBH4) or other strong reducing agents.
Oxidation: It can be oxidized to produce various compounds. For instance, treatment with mild oxidizing agents like potassium permanganate (KMnO4) can lead to the formation of adipic acid, a six-carbon dicarboxylic acid.
Amidation: You can perform an amidation reaction to form amides. This reaction typically involves the reaction of piperidine-2,6-dione with primary or secondary amines, yielding piperidine-2,6-dione amides.
Cyclization: Depending on the reaction conditions and reagents, piperidine-2,6-dione can undergo intramolecular reactions, leading to the formation of cyclic compounds. For example, it can be used as a starting material for the synthesis of various heterocyclic compounds.
Substitution Reactions: Piperidine-2,6-dione can undergo nucleophilic addition reactions at its carbonyl groups with various nucleophiles. This can lead to the formation of different compounds.
Acid-Catalyzed Reactions: Under acidic conditions, it can undergo hydrolysis reactions, particularly at the carbonyl groups, yielding corresponding carboxylic acids.
Base-Catalyzed Reactions: Under basic conditions, it can undergo nucleophilic addition reactions at the carbonyl groups, forming various products.
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(S)-3-Aminopiperidine-2,6-dione hydrochloride
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