Home Chemistry Organic Building Blocks Iodides (2-Iodophenyl)Methanol
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—CH2OH).
Sandmeyer Reaction: Iodobenzene can undergo a Sandmeyer reaction, where it is treated with a copper(I) salt and a source of nitrogen. This leads to the replacement of the iodine atom with a new functional group, such as an 【amine|https://www.ambeed.com/amines.html】, 【azide|https://www.ambeed.com/azides.html】, or 【cyanide|https://www.ambeed.com/nitriles.html】.
Cyanation: Phenylmethanol can react with a cyanide source to form benzyl cyanides (benzyl nitriles) in the presence of a base.
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(2-Iodo-5-(trifluoromethyl)phenyl)methanol
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(2-Iodo-4-(trifluoromethyl)phenyl)methanol
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