Home Chemistry Organic Building Blocks Chlorides 1-Chloro-2-Isothiocyanatobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—N=C=S).
Reduction: Chlorobenzene can be reduced to form cyclohexane under certain conditions, often using strong reducing agents like sodium in the presence of 【alcohol|https://www.ambeed.com/alcohols.html】.
Multicomponent Reaction: Isothiocyanatobenzene can participate in the Ugi reaction, a multicomponent reaction involving an 【isocyanide|https://www.ambeed.com/isocyanides.html】, an 【aldehyde|https://www.ambeed.com/aldehydes.html】 or 【ketone|https://www.ambeed.com/ketones.html】, an 【amine|https://www.ambeed.com/amines.html】, and a 【carboxylic acid|https://www.ambeed.com/carboxylic-acids.html】. This reaction forms a product known as a Ugi adduct.
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