Home Chemistry Organic Building Blocks Fluorinated Building Blocks 2-(2-Fluorophenyl)Acetic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH2COOH).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Amide Formation: It can react with 【amines|https://www.ambeed.com/amines.html】 to form 【Amides|https://www.ambeed.com/amides.html】 in the presence of suitable activating agents or reagents. Reaction: 2-Phenylacetic acid + amine → Amide + Water
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6-Chloro-2-fluoro-3-methoxyphenylacetic acid
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4-(Carboxymethyl)-3-fluorobenzeneboronic acid
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2-Fluoro-4-(trifluoromethyl)phenylacetic acid
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2-(2-(Difluoromethoxy)-6-fluorophenyl)acetic acid
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2-(2-Fluoro-5-methoxyphenyl)acetic acid
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2-(2-Fluoro-5-(trifluoromethyl)phenyl)acetic acid
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