Home Chemistry Organic Building Blocks Aryls 4-(Phenylsulfonyl)Morpholine
Nucleophilic Substitution: The sulfonyl group (SO2Ph) is an electrophilic functional group. It can undergo nucleophilic substitution reactions. Nucleophiles, such as amines or thiols, can displace the phenylsulfonyl group, leading to the formation of new compounds.
Acid-Catalyzed Hydrolysis: 4-(phenylsulfonyl)morpholine can undergo hydrolysis under acidic conditions. This can result in the cleavage of the sulfonyl group and the formation of the corresponding acid and morpholine.
Reduction: The phenylsulfonyl group can be reduced to a phenylsulfanyl (phenylthio) group using reducing agents such as sodium borohydride (NaBH4) or hydrogen gas in the presence of a suitable catalyst.
Acylation: The amino group of morpholine can undergo acylation reactions with acylating agents, such as acyl chlorides or anhydrides, to form amides.
Oxidation: The phenylsulfonyl group can be oxidized under certain conditions to convert it to a sulfoxide or sulfone.
Grignard Reaction: 4-(phenylsulfonyl)morpholine can react with Grignard reagents to form new compounds through nucleophilic addition.
Ring Opening Reactions: Depending on the reaction conditions and reagents, the morpholine ring can undergo ring-opening reactions, leading to the formation of open-chain compounds.
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4-(Morpholine-4-sulfonyl)-benzoyl chloride
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(3-(Morpholinosulfonyl)phenyl)boronic acid
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4-((2-(Bromomethyl)phenyl)sulfonyl)morpholine
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4-((3-Bromo-4-methylphenyl)sulfonyl)morpholine
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4-((5-Bromo-2-methoxyphenyl)sulfonyl)morpholine
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4-[(Morpholin-4-yl)sulphonyl]benzeneboronic acid
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(2-Methyl-5-(morpholinosulfonyl)phenyl)boronic acid
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(2-Methyl-4-(morpholinosulfonyl)phenyl)boronic acid
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(4-methoxy-3-(morpholinosulfonyl)phenyl)boronic acid
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