Chemistry Organic building blocks Bromides 2-bromo-6-chlorophenol

2-bromo-6-chlorophenol

These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—OH,—Cl).

Grignard Reaction: Bromobenzene can react with a Grignard reagent (organomagnesium compound) to form a new carbon-carbon bond, leading to the introduction of various functional groups.
Reduction: Phenol can be reduced to form cyclohexanone or cyclohexanol using reducing agents.
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.

Further Reading:

Framework+−

(1-bromoethyl)benzene (2,2-dibromovinyl)benzene (2-(4-bromophenyl)ethene-1,1,2-triyl)tribenzene (2-bromo-6-fluorophenyl)methanol (2-bromoethyl)benzene (2-bromophenyl)(phenyl)methanone (2-bromophenyl)boronic acid (2-bromophenyl)hydrazine (2-bromophenyl)methanamine (2-bromophenyl)methanol (3-bromo-2-fluorophenyl)boronic acid (3-bromo-2-methoxyphenyl)boronic acid (3-bromophenyl)boronic acid (3-bromopropyl)benzene (3-bromopyridin-2-yl)methanol (4-bromophenyl)(phenyl)methanone (5-bromopyridin-2-yl)methanamine (5-bromopyridin-2-yl)methanol (bromoethynyl)benzene (dibromomethyl)benzene (e)-1-bromo-4-styrylbenzene 1,2,3-tribromobenzene 1,2,4-tribromobenzene 1,2-dibromo-3-chlorobenzene 1,2-dibromo-3-fluorobenzene 1,2-dibromo-3-methylbenzene 1,2-dibromo-4-fluorobenzene 1,2-dibromobenzene 1,3-dibromo-2,4-difluorobenzene 1,3-dibromo-2,4-dimethylbenzene 1,3-dibromo-2-chlorobenzene 1,3-dibromo-2-fluorobenzene 1,3-dibromo-2-iodobenzene 1,3-dibromo-2-methoxybenzene 1,3-dibromo-2-methylbenzene 1,3-dibromo-2-nitrobenzene 1,4-dibromo-2-iodobenzene 1-(2-bromophenyl)ethan-1-amine 1-(2-bromophenyl)ethan-1-one 1-(5-bromopyridin-2-yl)piperazine 1-(azetidin-1-yl)-2-bromoethan-1-one 1-(benzyloxy)-2-bromobenzene 1-(benzyloxy)-3-bromobenzene 1-(benzyloxy)-4-bromobenzene 1-(bromomethyl)-2-iodobenzene 1-(bromomethyl)-2-methoxybenzene 1-(bromomethyl)-2-methylbenzene 1-(bromomethyl)-2-nitrobenzene 1-(bromomethyl)-3-methylbenzene 1-benzyl-3-bromobenzene 1-benzyl-4-bromo-1h-pyrazole 1-bromo-2,3-dichlorobenzene 1-bromo-2,3-difluorobenzene 1-bromo-2,3-dimethoxybenzene 1-bromo-2,3-dimethylbenzene 1-bromo-2,4-difluorobenzene 1-bromo-2-(bromomethyl)benzene 1-bromo-2-(difluoromethyl)benzene 1-bromo-2-(methylsulfonyl)benzene 1-bromo-2-(tert-butyl)benzene 1-bromo-2-(trifluoromethoxy)benzene 1-bromo-2-chloro-3-fluorobenzene 1-bromo-2-chloro-3-methoxybenzene 1-bromo-2-chloro-3-methylbenzene 1-bromo-2-chloro-4-nitrobenzene 1-bromo-2-cyclopropylbenzene 1-bromo-2-ethoxybenzene 1-bromo-2-ethylbenzene 1-bromo-2-fluoro-3-(trifluoromethyl)benzene 1-bromo-2-fluoro-3-methoxybenzene 1-bromo-2-fluoro-3-methylbenzene 1-bromo-2-fluoro-3-nitrobenzene 1-bromo-2-fluoro-4-nitrobenzene 1-bromo-2-iodobenzene 1-bromo-2-isopropylbenzene 1-bromo-2-phenoxybenzene 1-bromo-3-(trifluoromethyl)benzene 1-bromo-3-chloro-2-fluorobenzene 1-bromo-3-chloro-2-methylbenzene 1-bromo-3-cyclopropylbenzene 1-bromo-3-fluoro-2-iodobenzene 1-bromo-3-fluoro-2-methoxybenzene 1-bromo-3-fluoro-2-methylbenzene 1-bromo-3-fluoro-2-nitrobenzene 1-bromo-3-iodobenzene 1-bromo-3-methoxybenzene 1-bromo-3-methyl-2-nitrobenzene 1-bromo-3-nitrobenzene 1-bromo-3-phenoxybenzene 1-bromo-4-(phenylsulfonyl)benzene 1-bromo-4-chloro-2-fluorobenzene 1-bromo-4-fluoro-2-methoxybenzene 1-bromo-4-fluoro-2-methylbenzene 1-bromo-4-iodobenzene 1-bromo-4-phenoxybenzene 1-bromo-4-styrylbenzene 1-bromobicyclo[1.1.1]pentane 1-bromoisoquinoline 1-bromonaphthalene 2,3-dibromopyridine 2,4-dibromo-1-chlorobenzene 2,4-dibromo-1-fluorobenzene 2,4-dibromo-1-methoxybenzene 2,4-dibromoaniline 2,4-dibromophenol 2,4-dibromopyridine 2,4-dibromothiazole 2,5-dibromopyrazine 2,5-dibromopyridine 2,5-dibromothiazole 2,5-dibromothiophene 2,6-dibromo-3-fluoropyridine 2,6-dibromoaniline 2,6-dibromobenzaldehyde 2,6-dibromobenzonitrile 2,6-dibromophenol 2,6-dibromopyrazine 2,6-dibromopyridin-4-amine 2,6-dibromopyridine 2-(2-bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(2-bromophenyl)acetic acid 2-(2-bromophenyl)acetonitrile 2-(4-bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(bromomethyl)furan 2-(bromomethyl)pyridine 2-amino-3-bromobenzoic acid 2-amino-3-bromobenzonitrile 2-amino-3-bromophenol 2-amino-6-bromophenol 2-bromo-1,1'-biphenyl 2-bromo-1,3,4-thiadiazole 2-bromo-1,3,4-trifluorobenzene 2-bromo-1,3,4-trimethylbenzene 2-bromo-1,3-dichlorobenzene 2-bromo-1,3-difluorobenzene 2-bromo-1,3-dimethoxybenzene 2-bromo-1,3-dimethylbenzene 2-bromo-1,4-dichlorobenzene 2-bromo-1,4-difluorobenzene 2-bromo-1,4-dimethoxybenzene 2-bromo-1,4-dimethylbenzene 2-bromo-1-chloro-3-fluorobenzene 2-bromo-1-chloro-4-fluorobenzene 2-bromo-1-chloro-4-methylbenzene 2-bromo-1-chloro-4-nitrobenzene 2-bromo-1-fluoro-3-nitrobenzene 2-bromo-1-fluoro-4-(trifluoromethyl)benzene 2-bromo-1-fluoro-4-methoxybenzene 2-bromo-1-fluoro-4-methylbenzene 2-bromo-1-fluoro-4-nitrobenzene 2-bromo-1-methoxy-3-methylbenzene 2-bromo-1-methoxy-4-methylbenzene 2-bromo-1-methyl-4-nitrobenzene 2-bromo-1h-benzo[d]imidazole 2-bromo-1h-imidazole 2-bromo-1h-pyrrole 2-bromo-3-(trifluoromethyl)pyridine 2-bromo-3-chloroaniline 2-bromo-3-chloropyridine 2-bromo-3-fluoroaniline 2-bromo-3-fluoropyridine 2-bromo-3-hydroxybenzaldehyde 2-bromo-3-methoxybenzaldehyde 2-bromo-3-methoxypyridine 2-bromo-3-methylaniline 2-bromo-3-methylphenol 2-bromo-3-methylpyrazine 2-bromo-3-methylpyridine 2-bromo-3-nitrobenzoic acid 2-bromo-3-nitropyridine 2-bromo-4-(trifluoromethyl)aniline 2-bromo-4-chloro-1-fluorobenzene 2-bromo-4-chloro-1-methoxybenzene 2-bromo-4-chloro-1-methylbenzene 2-bromo-4-chloro-1-nitrobenzene 2-bromo-4-chloroaniline 2-bromo-4-chlorophenol 2-bromo-4-chloropyridine 2-bromo-4-fluoro-1-methoxybenzene 2-bromo-4-fluoro-1-methylbenzene 2-bromo-4-fluoro-1-nitrobenzene 2-bromo-4-fluoroaniline 2-bromo-4-fluorobenzaldehyde 2-bromo-4-fluorobenzoic acid 2-bromo-4-fluorobenzonitrile 2-bromo-4-fluorophenol 2-bromo-4-methoxy-1-nitrobenzene 2-bromo-4-methoxyaniline 2-bromo-4-methoxybenzaldehyde 2-bromo-4-methoxybenzoic acid 2-bromo-4-methylaniline 2-bromo-4-methylbenzoic acid 2-bromo-4-methylpyridine 2-bromo-4-methylthiazole 2-bromo-4-nitroaniline 2-bromo-5-(trifluoromethyl)pyridine 2-bromo-5-chloropyrazine 2-bromo-5-chloropyridine 2-bromo-5-fluoroaniline 2-bromo-5-fluorobenzaldehyde 2-bromo-5-fluorobenzoic acid 2-bromo-5-fluoropyridine 2-bromo-5-methoxybenzaldehyde 2-bromo-5-methoxypyridine 2-bromo-5-methylpyridine 2-bromo-5-methylthiazole 2-bromo-5-nitropyridine 2-bromo-6-(trifluoromethyl)aniline 2-bromo-6-(trifluoromethyl)pyridine 2-bromo-6-chloroaniline 2-bromo-6-chlorophenol 2-bromo-6-chloropyrazine 2-bromo-6-chloropyridine 2-bromo-6-fluoroaniline 2-bromo-6-fluorobenzaldehyde 2-bromo-6-fluorobenzoic acid 2-bromo-6-fluorobenzonitrile 2-bromo-6-fluorophenol 2-bromo-6-fluoropyridine 2-bromo-6-iodoaniline 2-bromo-6-methoxyaniline 2-bromo-6-methoxyphenol 2-bromo-6-methoxypyridine 2-bromo-6-methylaniline 2-bromo-6-methylbenzoic acid 2-bromo-6-methylphenol 2-bromo-6-methylpyrazine 2-bromo-6-methylpyridine 2-bromo-6-nitroaniline 2-bromo-6-nitrophenol 2-bromo-6-phenylpyridine 2-bromo-9,9-diphenyl-9h-fluorene 2-bromo-9h-fluorene 2-bromo-[1,2,4]triazolo[1,5-a]pyridine 2-bromo-n,n-dimethylaniline 2-bromo-n-methylaniline 2-bromo-n-phenylacetamide 2-bromobenzene-1,3-diol 2-bromobenzene-1,4-diol 2-bromobenzenesulfonyl chloride 2-bromobenzo[d]thiazole 2-bromodibenzo[b,d]furan 2-bromofuran 2-bromoimidazo[1,2-a]pyridine 2-bromonaphthalene 2-bromonicotinic acid 2-bromooxazole 2-bromopyrazine 2-bromopyridin-3-amine 2-bromopyridin-3-ol 2-bromopyridine 2-bromopyridine 1-oxide 2-bromopyrimidine 2-bromoquinazoline 3,4-dibromoaniline 3,4-dibromophenol 3,5-dibromopyridine 3-(bromomethyl)pyridine 3-bromo-1,1'-biphenyl 3-bromo-1,5-naphthyridine 3-bromo-1-methyl-1h-pyrazole 3-bromo-1h-pyrrole 3-bromo-1h-pyrrolo[2,3-b]pyridine 3-bromo-1h-pyrrolo[3,2-b]pyridine 3-bromo-2-chlorobenzaldehyde 3-bromo-2-chlorobenzoic acid 3-bromo-2-chloropyridin-4-amine 3-bromo-2-chloropyridine 3-bromo-2-fluoroaniline 3-bromo-2-fluorobenzaldehyde 3-bromo-2-fluorobenzoic acid 3-bromo-2-fluorobenzonitrile 3-bromo-2-fluorophenol 3-bromo-2-fluoropyridine 3-bromo-2-hydroxybenzaldehyde 3-bromo-2-hydroxybenzoic acid 3-bromo-2-hydroxybenzonitrile 3-bromo-2-methoxypyridine 3-bromo-2-methylpyridine 3-bromo-4-chloroaniline 3-bromo-4-chlorobenzoic acid 3-bromo-4-chlorophenol 3-bromo-4-fluoroaniline 3-bromo-4-fluorobenzaldehyde 3-bromo-4-fluorobenzamide 3-bromo-4-fluorobenzoic acid 3-bromo-4-fluorophenol 3-bromo-4-hydroxybenzaldehyde 3-bromo-4-hydroxybenzoic acid 3-bromo-4-methoxyaniline 3-bromo-4-methoxybenzaldehyde 3-bromo-4-methoxybenzoic acid 3-bromo-4-methylaniline 3-bromo-4-methylbenzoic acid 3-bromo-4-methylpyridine 3-bromo-5'-phenyl-1,1':3',1''-terphenyl 3-bromo-5-chloropyridine 3-bromo-5-fluoropyridine 3-bromo-5-methylpyridine 3-bromo-5-nitropyridine 3-bromoaniline 3-bromoazetidine 3-bromobenzene-1,2-diamine 3-bromobenzene-1,2-diol 3-bromobenzo[b]thiophene 3-bromobenzoic acid 3-bromobenzonitrile 3-bromofuran 3-bromoimidazo[1,2-a]pyridine 3-bromoimidazo[1,2-a]pyrimidine 3-bromoisoquinoline 3-bromoisoxazole 3-bromopicolinic acid 3-bromopicolinonitrile 3-bromopyrazolo[1,5-a]pyrimidine 3-bromopyridazine 3-bromopyridin-2-amine 3-bromopyridin-2-ol 3-bromopyridine 1-oxide 3-bromopyrrolidine 3-bromothiophene 4-(bromomethyl)-1,1'-biphenyl 4-(bromomethyl)pyridine 4-bromo-1,5-naphthyridine 4-bromo-1-methyl-1h-pyrazole 4-bromo-1-phenyl-1h-imidazole 4-bromo-1-phenyl-1h-pyrazole 4-bromo-1h-benzo[d]imidazole 4-bromo-1h-indole 4-bromo-1h-pyrazolo[3,4-b]pyridine 4-bromo-1h-pyrrolo[2,3-b]pyridine 4-bromo-2-chloro-1-iodobenzene 4-bromo-2-chloropyridine 4-bromo-2-fluoro-1-iodobenzene 4-bromo-2-fluoropyridine 4-bromo-2-iodoaniline 4-bromo-2-methoxypyridine 4-bromo-3-(trifluoromethyl)aniline 4-bromo-3-chloroaniline 4-bromo-3-fluoroaniline 4-bromo-3-methylaniline 4-bromo-3-methylpyridine 4-bromo-3-nitroaniline 4-bromo-n,n-diphenylaniline 4-bromo-n-phenylaniline 4-bromo-n-phenylbenzenesulfonamide 4-bromobenzo[c][1,2,5]thiadiazole 4-bromobenzo[d][1,3]dioxole 4-bromobenzo[d]thiazole 4-bromobenzofuran 4-bromoindoline 4-bromoisoindolin-1-one 4-bromoisoquinolin-1(2h)-one 4-bromoisoquinoline 4-bromopyridazine 4-bromopyridine 4-bromopyrimidine 4-bromothiazole 5-bromo-1,2,3,4-tetrahydroisoquinoline 5-bromo-1-methyl-1h-indole 5-bromo-1h-1,2,4-triazole 5-bromo-1h-benzo[d][1,2,3]triazole 5-bromo-1h-benzo[d]imidazole 5-bromo-1h-indazole 5-bromo-1h-pyrazole 5-bromo-1h-pyrazolo[3,4-b]pyridine 5-bromo-1h-pyrazolo[3,4-c]pyridine 5-bromo-1h-pyrrolo[2,3-b]pyridine 5-bromo-2,3-dihydro-1h-indene 5-bromo-2,3-dihydrobenzofuran 5-bromo-2-chloro-4-methylpyridine 5-bromo-2-chloropyridine 5-bromo-2-chloropyrimidine 5-bromo-2-fluoropyridine 5-bromo-2-methoxypyridine 5-bromo-2-methylpyridine 5-bromo-2-methylpyrimidine 5-bromo-2-phenylpyridine 5-bromo-4-methylpyridin-2-amine 5-bromo-6-chloropyridin-2-amine 5-bromo-7h-pyrrolo[2,3-d]pyrimidine 5-bromobenzo[b]thiophene 5-bromobenzo[d][1,3]dioxole 5-bromobenzo[d]oxazole 5-bromoimidazo[1,2-a]pyridine 5-bromoindoline 5-bromoisoindolin-1-one 5-bromoisoquinoline 5-bromonicotinaldehyde 5-bromonicotinic acid 5-bromonicotinonitrile 5-bromopicolinic acid 5-bromopicolinonitrile 5-bromopyrazin-2-ol 5-bromopyridin-2-amine 5-bromopyridin-2-ol 5-bromopyridin-3-amine 5-bromopyridin-3-ol 5-bromoquinoxaline 5-bromothiazole 6-bromo-1,2,3,4-tetrahydroisoquinoline 6-bromo-1,2,3,4-tetrahydroquinoline 6-bromo-1-methyl-1h-indole 6-bromo-1h-indazole 6-bromo-1h-indole 6-bromo-1h-pyrazolo[4,3-b]pyridine 6-bromo-1h-pyrrolo[2,3-b]pyridine 6-bromo-1h-pyrrolo[3,2-b]pyridine 6-bromo-1h-pyrrolo[3,2-c]pyridine 6-bromo-3,4-dihydro-2h-benzo[b][1,4]oxazine 6-bromo-3,4-dihydroisoquinolin-1(2h)-one 6-bromo-3,4-dihydroquinolin-2(1h)-one 6-bromo-[1,2,4]triazolo[1,5-a]pyridine 6-bromo-[1,2,4]triazolo[4,3-a]pyridine 6-bromobenzo[b]thiophene 6-bromobenzo[d]oxazole 6-bromobenzo[d]thiazole 6-bromochroman-4-one 6-bromoimidazo[1,2-a]pyrimidine 6-bromoindoline-2,3-dione 6-bromoisoindolin-1-one 6-bromoisoquinoline 6-bromonicotinaldehyde 6-bromonicotinic acid 6-bromonicotinonitrile 6-bromopicolinic acid 6-bromopyrazolo[1,5-a]pyrimidine 6-bromopyridin-2-amine 6-bromopyridin-3-amine 6-bromopyridin-3-ol 6-bromoquinazoline 6-bromoquinoxaline 7-bromo-1,2,3,4-tetrahydroisoquinoline 7-bromo-1h-indazole 7-bromo-1h-indole 7-bromo-1h-pyrrolo[2,3-c]pyridine 7-bromo-2,3-dihydrobenzofuran 7-bromo-3,4-dihydro-2h-benzo[b][1,4]oxazine 7-bromo-3,4-dihydroisoquinolin-1(2h)-one 7-bromo-3,4-dihydronaphthalen-1(2h)-one 7-bromobenzo[b]thiophene 7-bromobenzo[d]thiazole 7-bromobenzofuran 7-bromochromane 7-bromoindoline 7-bromoisoquinoline 8-bromo-[1,2,4]triazolo[1,5-a]pyridine 8-bromochromane 8-bromoimidazo[1,2-a]pyridine 8-bromoisoquinoline 8-bromoquinazoline 9-bromoanthracene Bromocyclohexane Ethyl 2-bromo-2-phenylacetate Methyl 2-(2-bromophenyl)acetate Methyl 2-bromo-2-phenylacetate Methyl 2-bromo-3-nitrobenzoate Methyl 2-bromo-5-fluorobenzoate Methyl 2-bromo-6-fluorobenzoate Methyl 2-bromo-6-methylbenzoate Methyl 2-bromobenzoate Methyl 3-(bromomethyl)benzoate Methyl 3-bromo-4-chlorobenzoate Methyl 3-bromo-4-fluorobenzoate Methyl 3-bromo-4-methoxybenzoate Methyl 3-bromo-4-methylbenzoate Methyl 3-bromobenzoate Methyl 3-bromopicolinate Methyl 4-amino-3-bromobenzoate Methyl 5-amino-2-bromobenzoate Methyl 6-bromonicotinate N-(2-benzoylphenyl)-2-bromoacetamide Tert-butyl 2-(bromomethyl)morpholine-4-carboxylate Tert-butyl 3-bromo-1h-indole-1-carboxylate Tert-butyl 3-bromopiperidine-1-carboxylate

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2,2-dibromovinyl 2-bromo-acetamide 2-bromoethanone 2-bromoethoxy 2-bromoethyl 3-bromopropyl 4-bromobutoxy 6-bromohexyl Benzothiazolyl-bromide Benzothiophene-bromide Bromindan-one Bromo-benzene-diol Bromo-benzimidazole Bromo-benzocarbazole Bromo-benzooxazin-one Bromo-benzooxazine Bromo-carbazole Bromo-carboxylate Bromo-chloro-benzene Bromo-chromen Bromo-ethyl-indazole Bromo-fluorene Bromo-fluoro-indazole Bromo-fluoro-nitro-benzene Bromo-fluorobenzene Bromo-hydroxy Bromo-imidazole Bromo-imidazopyridine Bromo-indazole Bromo-indazole-carboxylate Bromo-indene Bromo-indole-carboxylate Bromo-methoxy-indazole Bromo-methyl-imidazole Bromo-methyl-indole Bromo-methyl-pyrazole Bromo-methylbenzene Bromo-naphtho-benzofuran Bromo-naphthyridin-one Bromo-naphthyridine Bromo-nitrobenzene Bromo-pyrazol-amide Bromo-pyrazole-carboxylate Bromo-pyrazolopyridine Bromo-pyrrolopyridine Bromo-pyrrolopyrimidine Bromo-thiadiazole Bromo-triazole Bromo-trifluoromethyl-pyridine Bromoacetate Bromoacetyl Bromoaniline Bromoanthracene Bromoanthracene Bromobenzaldehyde Bromobenzamide Bromobenzene Bromobenzimidamide Bromobenzofuran Bromobenzoic Bromobenzotrifluoride Bromobenzyl Bromobut Bromobut Bromobutoxy Bromobutoxy Bromobutyl Bromobutyl Bromochroman Bromochroman Bromocinnoline Bromocyclobutanecarboxylate Bromocyclopropanecarboxylate Bromoethoxy Bromoethoxy Bromoethyl Bromoethyl Bromoethynyl Bromohexyl Bromohexyl Bromoindole Bromoisobenzofuran Bromoisopropyl-indazole Bromomethyl Bromomethyl-indazole Bromonaphthalene Bromonicotinaldehyde Bromonicotinamide Bromooctyl Bromooxazole Bromopentyl Bromopentyl Bromophenyl-boronate Bromophthalazin Bromopiperidine Bromopropane Bromopropane Bromopropoxy Bromopropoxy Bromopropyl Bromopropyl Bromopyrazine Bromopyrazolo Bromopyridazine Bromopyridine Bromopyridine-boronate Bromopyrimidine Bromopyrrole-carboxylate Bromoquinazoline Bromoquinoline Bromoquinoxaline Bromothiazole Bromothiochroman Bromothiochroman Bromothiophene Bromovinyl Dibromo Dibromo Dibromoanthracene Dibromoanthracene Dibromobenzaldehyde Dibromobenzonitrile Dibromomethyl Dibromomethyl Dibromopropoxy Dibromopropoxy Dibromoquinoline Ethyl 2-bromo-acetate Fluoren-one Indene-bromide Methyl 2-bromo-acetate Tert-butoxybromobenzene Tert-butylbromobenzene Tetrabromo Tetrabromo Tetrahydroisoquinoline-bromide Tetrahydroquinoline-bromide Tribromo Tribromo Tribromomethyl

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