Home Chemistry Organic Building Blocks Fluorinated Building Blocks 3,4-Difluorophenol
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OH).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Hydroxylation: Phenol can be hydroxylated using various oxidizing agents to introduce additional hydroxyl groups onto the ring.
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4,5-Difluoro-2-hydroxyphenylboronic acid
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(2,3-Difluoro-6-hydroxyphenyl)boronic acid
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