The Fucosyltransferase family comprises multiple key enzymes responsible for catalyzing the fucosylation of carbohydrate structures on the cell surface. Primarily active within the Golgi apparatus, these enzymes transfer fucose units to glycoproteins and glycolipids, thereby affecting crucial biological processes such as cell recognition, adhesion, and signal transduction. The gene expression of Fucosyltransferase is tissue-specific, and changes in its activity and expression levels are closely related to various diseases, including cancer and inflammation. Moreover, mutations or dysregulation in gene expression can lead to abnormal glycan structures, affecting intercellular communication and immune responses.