Home Chemistry Organic Building Blocks Bromides 3-Bromo-2-Hydroxybenzonitrile
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Br,—OH,—C≡N).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Hydroxylation: Phenol can be hydroxylated using various oxidizing agents to introduce additional hydroxyl groups onto the ring.
Cyanohydrin Formation: Benzonitrile can react with carbonyl compounds in the presence of hydrogen cyanide (HCN) to form cyanohydrin compounds.
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